Abstract
An optical technique based on laser-induced bone autofluorescence was used to characterize intact cortical bone and correlate the results with mechanical test results. The optical system consisted of a nitrogen laser for excitation and a fiber-optic probe to deliver the laser light and acquire the fluorescence spectrum. An unprecedented progressive increase in the width of the autofluorescence peak with aging was observed. It was found that the fracture toughness decreased with age. Since the autofluorescence originates only from the organic phase of the bone, the changes in the mechanical properties of the bone may be attributed to organic phase changes manifested in the fluorescence spectrum.
| Original language | English (US) |
|---|---|
| Title of host publication | Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium |
| Editors | Anon |
| Place of Publication | St. Louis Park, MN, United States |
| Publisher | Soc for Biomaterials |
| Pages | 920 |
| Number of pages | 1 |
| Volume | 1 |
| State | Published - 1996 |
| Externally published | Yes |
| Event | Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can Duration: May 29 1996 → Jun 2 1996 |
Other
| Other | Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) |
|---|---|
| City | Toronto, Can |
| Period | 5/29/96 → 6/2/96 |
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ASJC Scopus subject areas
- Materials Science(all)
Cite this
Novel optical technique to characterize intact cortical bone. / Kovach, I. S.; Wang, X.; Agrawal, C. M.; Richards-Kortum, R.; Athanasiou, K. A.
Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. ed. / Anon. Vol. 1 St. Louis Park, MN, United States : Soc for Biomaterials, 1996. p. 920.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Novel optical technique to characterize intact cortical bone
AU - Kovach, I. S.
AU - Wang, X.
AU - Agrawal, C. M.
AU - Richards-Kortum, R.
AU - Athanasiou, K. A.
PY - 1996
Y1 - 1996
N2 - An optical technique based on laser-induced bone autofluorescence was used to characterize intact cortical bone and correlate the results with mechanical test results. The optical system consisted of a nitrogen laser for excitation and a fiber-optic probe to deliver the laser light and acquire the fluorescence spectrum. An unprecedented progressive increase in the width of the autofluorescence peak with aging was observed. It was found that the fracture toughness decreased with age. Since the autofluorescence originates only from the organic phase of the bone, the changes in the mechanical properties of the bone may be attributed to organic phase changes manifested in the fluorescence spectrum.
AB - An optical technique based on laser-induced bone autofluorescence was used to characterize intact cortical bone and correlate the results with mechanical test results. The optical system consisted of a nitrogen laser for excitation and a fiber-optic probe to deliver the laser light and acquire the fluorescence spectrum. An unprecedented progressive increase in the width of the autofluorescence peak with aging was observed. It was found that the fracture toughness decreased with age. Since the autofluorescence originates only from the organic phase of the bone, the changes in the mechanical properties of the bone may be attributed to organic phase changes manifested in the fluorescence spectrum.
UR - http://www.scopus.com/inward/record.url?scp=0030388176&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030388176&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0030388176
VL - 1
SP - 920
BT - Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
A2 - Anon, null
PB - Soc for Biomaterials
CY - St. Louis Park, MN, United States
ER -