Novel optical technique to characterize intact cortical bone

I. S. Kovach; X. Wang; C. M. Agrawal; R. Richards-Kortum; K. A. Athanasiou

Novel optical technique to characterize intact cortical bone

I. S. Kovach, X. Wang, C. M. Agrawal, R. Richards-Kortum, K. A. Athanasiou

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

An optical technique based on laser-induced bone autofluorescence was used to characterize intact cortical bone and correlate the results with mechanical test results. The optical system consisted of a nitrogen laser for excitation and a fiber-optic probe to deliver the laser light and acquire the fluorescence spectrum. An unprecedented progressive increase in the width of the autofluorescence peak with aging was observed. It was found that the fracture toughness decreased with age. Since the autofluorescence originates only from the organic phase of the bone, the changes in the mechanical properties of the bone may be attributed to organic phase changes manifested in the fluorescence spectrum.

Original language	English (US)
Title of host publication	Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
Editors	Anon
Place of Publication	St. Louis Park, MN, United States
Publisher	Soc for Biomaterials
Pages	920
Number of pages	1
Volume	1
State	Published - 1996
Externally published	Yes
Event	Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can Duration: May 29 1996 → Jun 2 1996

Other

Other	Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
City	Toronto, Can
Period	5/29/96 → 6/2/96

ASJC Scopus subject areas

Materials Science(all)

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Novel optical technique to characterize intact cortical bone. / Kovach, I. S.; Wang, X.; Agrawal, C. M.; Richards-Kortum, R.; Athanasiou, K. A.

Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. ed. / Anon. Vol. 1 St. Louis Park, MN, United States : Soc for Biomaterials, 1996. p. 920.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kovach, IS, Wang, X, Agrawal, CM, Richards-Kortum, R & Athanasiou, KA 1996, Novel optical technique to characterize intact cortical bone. in Anon (ed.), Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. vol. 1, Soc for Biomaterials, St. Louis Park, MN, United States, pp. 920, Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2), Toronto, Can, 5/29/96.

Kovach, I. S. ; Wang, X. ; Agrawal, C. M. ; Richards-Kortum, R. ; Athanasiou, K. A. / Novel optical technique to characterize intact cortical bone. Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. editor / Anon. Vol. 1 St. Louis Park, MN, United States : Soc for Biomaterials, 1996. pp. 920

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abstract = "An optical technique based on laser-induced bone autofluorescence was used to characterize intact cortical bone and correlate the results with mechanical test results. The optical system consisted of a nitrogen laser for excitation and a fiber-optic probe to deliver the laser light and acquire the fluorescence spectrum. An unprecedented progressive increase in the width of the autofluorescence peak with aging was observed. It was found that the fracture toughness decreased with age. Since the autofluorescence originates only from the organic phase of the bone, the changes in the mechanical properties of the bone may be attributed to organic phase changes manifested in the fluorescence spectrum.",

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year = "1996",

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booktitle = "Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium",

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AU - Athanasiou, K. A.

PY - 1996

Y1 - 1996

N2 - An optical technique based on laser-induced bone autofluorescence was used to characterize intact cortical bone and correlate the results with mechanical test results. The optical system consisted of a nitrogen laser for excitation and a fiber-optic probe to deliver the laser light and acquire the fluorescence spectrum. An unprecedented progressive increase in the width of the autofluorescence peak with aging was observed. It was found that the fracture toughness decreased with age. Since the autofluorescence originates only from the organic phase of the bone, the changes in the mechanical properties of the bone may be attributed to organic phase changes manifested in the fluorescence spectrum.

AB - An optical technique based on laser-induced bone autofluorescence was used to characterize intact cortical bone and correlate the results with mechanical test results. The optical system consisted of a nitrogen laser for excitation and a fiber-optic probe to deliver the laser light and acquire the fluorescence spectrum. An unprecedented progressive increase in the width of the autofluorescence peak with aging was observed. It was found that the fracture toughness decreased with age. Since the autofluorescence originates only from the organic phase of the bone, the changes in the mechanical properties of the bone may be attributed to organic phase changes manifested in the fluorescence spectrum.

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BT - Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium

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PB - Soc for Biomaterials

CY - St. Louis Park, MN, United States

T2 - Proceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)

Y2 - 29 May 1996 through 2 June 1996

ER -

Novel optical technique to characterize intact cortical bone

Abstract

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