Novel optical technique to characterize intact cortical bone

I. S. Kovach, X. Wang, C. M. Agrawal, R. Richards-Kortum, K. A. Athanasiou

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


An optical technique based on laser-induced bone autofluorescence was used to characterize intact cortical bone and correlate the results with mechanical test results. The optical system consisted of a nitrogen laser for excitation and a fiber-optic probe to deliver the laser light and acquire the fluorescence spectrum. An unprecedented progressive increase in the width of the autofluorescence peak with aging was observed. It was found that the fracture toughness decreased with age. Since the autofluorescence originates only from the organic phase of the bone, the changes in the mechanical properties of the bone may be attributed to organic phase changes manifested in the fluorescence spectrum.

Original languageEnglish (US)
Title of host publicationTransactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
Editors Anon
Place of PublicationSt. Louis Park, MN, United States
PublisherSoc for Biomaterials
Number of pages1
StatePublished - 1996
Externally publishedYes
EventProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can
Duration: May 29 1996Jun 2 1996


OtherProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
CityToronto, Can

ASJC Scopus subject areas

  • Materials Science(all)


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