Novel modifications in RNA

Kelly Phelps, Alexi Morris, Peter A. Beal

Research output: Contribution to journalArticle

53 Scopus citations


The past several years have seen numerous reports of new chemical modifications for use in RNA. In addition, in that time period, we have seen the discovery of several previously unknown naturally occurring modifications that impart novel properties on the parent RNAs. In this review, we describe recent discoveries in these areas with a focus on RNA modifications that introduce spectroscopic tags, reactive handles, or new recognition properties.

Original languageEnglish (US)
Pages (from-to)100-109
Number of pages10
JournalACS Chemical Biology
Issue number1
StatePublished - Jan 20 2012


ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine

Cite this

Phelps, K., Morris, A., & Beal, P. A. (2012). Novel modifications in RNA. ACS Chemical Biology, 7(1), 100-109.