Novel gastric helicobacters and oral campylobacters are present in captive and wild cetaceans

Cinthia G. Goldman, Mario J. Matteo, Julio D. Loureiro, Marisa Almuzara, Claudia Barberis, Carlos Vay, Mariana Catalano, Sergio Rodríguez Heredia, Paula Mantero, Jose R. Boccio, Marcela B. Zubillaga, Graciela A. Cremaschi, Jay V Solnick, Guillermo I. Perez-Perez, Martin J. Blaser

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The mammalian gastric and oral mucosa may be colonized by mixed Helicobacter and Campylobacter species, respectively, in individual animals. To better characterize the presence and distribution of Helicobacter and Campylobacter among marine mammals, we used PCR and 16S rDNA sequence analysis to examine gastric and oral samples from ten dolphins (Tursiops gephyreus), one killer whale (Orcinus orca), one false killer whale (Pseudorca crassidens), and three wild La Plata river dolphins (Pontoporia blainvillei). Helicobacter spp. DNA was widely distributed in gastric and oral samples from both captive and wild cetaceans. Phylogenetic analysis demonstrated two Helicobacter sequence clusters, one closely related to H. cetorum, a species isolated from dolphins and whales in North America. The second related cluster was to sequences obtained from dolphins in Australia and to gastric non-H. pylori helicobacters, and may represent a novel taxonomic group. Dental plaque sequences from four dolphins formed a third cluster within the Campylobacter genus that likely represents a novel species isolated from marine mammals. Identification of identical Helicobacter spp. DNA sequences from dental plaque, saliva and gastric fluids from the same hosts, suggests that the oral cavity may be involved in transmission. These results demonstrate that Helicobacter and Campylobacter species are commonly distributed in marine mammals, and identify taxonomic clusters that may represent novel species.

Original languageEnglish (US)
Pages (from-to)138-145
Number of pages8
JournalVeterinary Microbiology
Volume152
Issue number1-2
DOIs
StatePublished - Aug 26 2011

Fingerprint

Helicobacter
Dolphins
Campylobacter
dolphins
mouth
Stomach
stomach
marine mammals
Killer Whale
Orcinus orca
Mammals
Dental Plaque
teeth
digestive tract mucosa
Tursiops
Helicobacter pylori
gastric mucosa
Whales
saliva
whales

Keywords

  • Campylobacter
  • Cetaceans
  • Gastritis
  • Helicobacter
  • Marine mammals

ASJC Scopus subject areas

  • Microbiology
  • veterinary(all)

Cite this

Goldman, C. G., Matteo, M. J., Loureiro, J. D., Almuzara, M., Barberis, C., Vay, C., ... Blaser, M. J. (2011). Novel gastric helicobacters and oral campylobacters are present in captive and wild cetaceans. Veterinary Microbiology, 152(1-2), 138-145. https://doi.org/10.1016/j.vetmic.2011.04.023

Novel gastric helicobacters and oral campylobacters are present in captive and wild cetaceans. / Goldman, Cinthia G.; Matteo, Mario J.; Loureiro, Julio D.; Almuzara, Marisa; Barberis, Claudia; Vay, Carlos; Catalano, Mariana; Heredia, Sergio Rodríguez; Mantero, Paula; Boccio, Jose R.; Zubillaga, Marcela B.; Cremaschi, Graciela A.; Solnick, Jay V; Perez-Perez, Guillermo I.; Blaser, Martin J.

In: Veterinary Microbiology, Vol. 152, No. 1-2, 26.08.2011, p. 138-145.

Research output: Contribution to journalArticle

Goldman, CG, Matteo, MJ, Loureiro, JD, Almuzara, M, Barberis, C, Vay, C, Catalano, M, Heredia, SR, Mantero, P, Boccio, JR, Zubillaga, MB, Cremaschi, GA, Solnick, JV, Perez-Perez, GI & Blaser, MJ 2011, 'Novel gastric helicobacters and oral campylobacters are present in captive and wild cetaceans', Veterinary Microbiology, vol. 152, no. 1-2, pp. 138-145. https://doi.org/10.1016/j.vetmic.2011.04.023
Goldman CG, Matteo MJ, Loureiro JD, Almuzara M, Barberis C, Vay C et al. Novel gastric helicobacters and oral campylobacters are present in captive and wild cetaceans. Veterinary Microbiology. 2011 Aug 26;152(1-2):138-145. https://doi.org/10.1016/j.vetmic.2011.04.023
Goldman, Cinthia G. ; Matteo, Mario J. ; Loureiro, Julio D. ; Almuzara, Marisa ; Barberis, Claudia ; Vay, Carlos ; Catalano, Mariana ; Heredia, Sergio Rodríguez ; Mantero, Paula ; Boccio, Jose R. ; Zubillaga, Marcela B. ; Cremaschi, Graciela A. ; Solnick, Jay V ; Perez-Perez, Guillermo I. ; Blaser, Martin J. / Novel gastric helicobacters and oral campylobacters are present in captive and wild cetaceans. In: Veterinary Microbiology. 2011 ; Vol. 152, No. 1-2. pp. 138-145.
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