Abstract
Lung aging begins at birth. In this chapter, the normal development and aging process of the respiratory system is examined for the mouse, rat, dog, and rhesus monkey over the life span of each species. Few studies have quantitatively examined structural changes in the lungs that occur with aging. Age-related changes in the respiratory system are described for the parenchymal or alveolar gas exchange portions of the lungs. More limited information is provided for cellular and structural changes in the aging process of the tracheobronchial tree.
Original language | English (US) |
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Title of host publication | The Lung: Development, Aging and the Environment: Second Edition |
Publisher | Elsevier Inc. |
Pages | 265-285 |
Number of pages | 21 |
ISBN (Print) | 9780127999418 |
DOIs | |
State | Published - Oct 23 2014 |
Keywords
- Airways
- Alveoli
- Dog
- Monkey
- Mouse
- Neonatal
- Parenchyma
- Rat
- Senescent
ASJC Scopus subject areas
- Medicine(all)
- Pharmacology, Toxicology and Pharmaceutics(all)