Normal Aging of the Lung

Kent E Pinkerton; Matt J. Herring; Dallas M. Hyde; Francis H Y Green

doi:10.1016/B978-0-12-799941-8.00014-6

Normal Aging of the Lung

Kent E Pinkerton, Matt J. Herring, Dallas M. Hyde, Francis H Y Green

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

Lung aging begins at birth. In this chapter, the normal development and aging process of the respiratory system is examined for the mouse, rat, dog, and rhesus monkey over the life span of each species. Few studies have quantitatively examined structural changes in the lungs that occur with aging. Age-related changes in the respiratory system are described for the parenchymal or alveolar gas exchange portions of the lungs. More limited information is provided for cellular and structural changes in the aging process of the tracheobronchial tree.

Original language	English (US)
Title of host publication	The Lung: Development, Aging and the Environment: Second Edition
Publisher	Elsevier Inc.
Pages	265-285
Number of pages	21
ISBN (Print)	9780127999418
DOIs	https://doi.org/10.1016/B978-0-12-799941-8.00014-6
State	Published - Oct 23 2014

Keywords

Airways
Alveoli
Dog
Monkey
Mouse
Neonatal
Parenchyma
Rat
Senescent

ASJC Scopus subject areas

Medicine(all)
Pharmacology, Toxicology and Pharmaceutics(all)

Access to Document

10.1016/B978-0-12-799941-8.00014-6

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abstract = "Lung aging begins at birth. In this chapter, the normal development and aging process of the respiratory system is examined for the mouse, rat, dog, and rhesus monkey over the life span of each species. Few studies have quantitatively examined structural changes in the lungs that occur with aging. Age-related changes in the respiratory system are described for the parenchymal or alveolar gas exchange portions of the lungs. More limited information is provided for cellular and structural changes in the aging process of the tracheobronchial tree.",

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AU - Herring, Matt J.

AU - Hyde, Dallas M.

AU - Green, Francis H Y

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AB - Lung aging begins at birth. In this chapter, the normal development and aging process of the respiratory system is examined for the mouse, rat, dog, and rhesus monkey over the life span of each species. Few studies have quantitatively examined structural changes in the lungs that occur with aging. Age-related changes in the respiratory system are described for the parenchymal or alveolar gas exchange portions of the lungs. More limited information is provided for cellular and structural changes in the aging process of the tracheobronchial tree.

KW - Airways

KW - Alveoli

KW - Dog

KW - Monkey

KW - Mouse

KW - Neonatal

KW - Parenchyma

KW - Rat

KW - Senescent

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