Norepinephrine-induced depolarization of skeletal muscle cells

Nancy Teskey; Barbara A Horwitz; John Horowitz

doi:10.1016/0014-2999(75)90120-X

Norepinephrine-induced depolarization of skeletal muscle cells

Nancy Teskey, Barbara A Horwitz, John Horowitz

Physiology and Membrane Biology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

I.v. administration of norepinephrine to anesthetized hamsters was followed by a significant depolarization of the cell membranes of skeletal muscle (gracilis anticus and sartorius). The occurrence of this depolarization is consistent with the suggestion that changes in ionic distribution across the cell membrane are associated with activation of non-shivering thermogenesis in muscle cells as has been proposed for brown adipocytes.

Original language	English (US)
Pages (from-to)	352-355
Number of pages	4
Journal	European Journal of Pharmacology
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/0014-2999(75)90120-X
State	Published - 1975

Keywords

Catecholamine
Heat production
Membrane depolarization
Non-shivering thermogenesis
Norepinephrine
Skeletal muscle

ASJC Scopus subject areas

Cellular and Molecular Neuroscience
Pharmacology

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title = "Norepinephrine-induced depolarization of skeletal muscle cells",

abstract = "I.v. administration of norepinephrine to anesthetized hamsters was followed by a significant depolarization of the cell membranes of skeletal muscle (gracilis anticus and sartorius). The occurrence of this depolarization is consistent with the suggestion that changes in ionic distribution across the cell membrane are associated with activation of non-shivering thermogenesis in muscle cells as has been proposed for brown adipocytes.",

keywords = "Catecholamine, Heat production, Membrane depolarization, Non-shivering thermogenesis, Norepinephrine, Skeletal muscle",

author = "Nancy Teskey and Horwitz, {Barbara A} and John Horowitz",

year = "1975",

doi = "10.1016/0014-2999(75)90120-X",

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pages = "352--355",

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T1 - Norepinephrine-induced depolarization of skeletal muscle cells

AU - Teskey, Nancy

AU - Horwitz, Barbara A

AU - Horowitz, John

PY - 1975

Y1 - 1975

N2 - I.v. administration of norepinephrine to anesthetized hamsters was followed by a significant depolarization of the cell membranes of skeletal muscle (gracilis anticus and sartorius). The occurrence of this depolarization is consistent with the suggestion that changes in ionic distribution across the cell membrane are associated with activation of non-shivering thermogenesis in muscle cells as has been proposed for brown adipocytes.

AB - I.v. administration of norepinephrine to anesthetized hamsters was followed by a significant depolarization of the cell membranes of skeletal muscle (gracilis anticus and sartorius). The occurrence of this depolarization is consistent with the suggestion that changes in ionic distribution across the cell membrane are associated with activation of non-shivering thermogenesis in muscle cells as has been proposed for brown adipocytes.

KW - Catecholamine

KW - Heat production

KW - Membrane depolarization

KW - Non-shivering thermogenesis

KW - Norepinephrine

KW - Skeletal muscle

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U2 - 10.1016/0014-2999(75)90120-X

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JO - European Journal of Pharmacology

JF - European Journal of Pharmacology

SN - 0014-2999

IS - 2

ER -

Norepinephrine-induced depolarization of skeletal muscle cells

Abstract

Keywords

ASJC Scopus subject areas

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