Abstract
I.v. administration of norepinephrine to anesthetized hamsters was followed by a significant depolarization of the cell membranes of skeletal muscle (gracilis anticus and sartorius). The occurrence of this depolarization is consistent with the suggestion that changes in ionic distribution across the cell membrane are associated with activation of non-shivering thermogenesis in muscle cells as has been proposed for brown adipocytes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 352-355 |
| Number of pages | 4 |
| Journal | European Journal of Pharmacology |
| Volume | 30 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1975 |
Keywords
- Catecholamine
- Heat production
- Membrane depolarization
- Non-shivering thermogenesis
- Norepinephrine
- Skeletal muscle
ASJC Scopus subject areas
- Cellular and Molecular Neuroscience
- Pharmacology
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Cite this
Teskey, N., Horwitz, B. A., & Horowitz, J. (1975). Norepinephrine-induced depolarization of skeletal muscle cells. European Journal of Pharmacology, 30(2), 352-355. https://doi.org/10.1016/0014-2999(75)90120-X