Nonpharmacologic, nonherbal management of menopause-associated vasomotor symptoms: An umbrella systematic review (protocol)

Karen M. Goldstein, Jennifer R. McDuffie, Megan Shepherd-Banigan, Deanna Befus, Remy R. Coeytaux, Megan G. Van Noord, Adam P. Goode, Varsha Masilamani, Soheir Adam, Avishek Nagi, John W. Williams

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Background: Vasomotor symptoms such as hot flashes and night sweats are a common concern of perimenopausal and postmenopausal women and are associated with a decreased quality of life. These symptoms can be effectively managed with hormone therapy, but safety concerns limit its use. Thus, understanding the effectiveness of nonpharmacologic therapies such as acupuncture or yoga is critical to managing these common symptoms in older women. Our review seeks to address the following question: In women with menopause-associated vasomotor symptoms, what are the effects on health-related quality of life, vasomotor symptoms, and adverse events of the following nonpharmacologic, nonherbal interventions as compared with any inactive control or active comparator: (a) acupuncture, (b) yoga, tai chi, and qigong, (c) structured exercise, and (d) meditation, mindfulness-based practices, and relaxation? Methods: We describe a protocol for an umbrella review approach, supplemented by evaluating randomized controlled trials (RCTs) published after the most recent good-quality systematic review for each of the eligible interventions. Specific interventions were chosen based on current literature and with input from a technical expert panel and organizational stakeholders. We will conduct a thorough literature search and perform a quality assessment of potentially included systematic reviews and RCTs. Discussion: Our umbrella review, supplemented by an additional search for eligible RCTs, aims to synthesize existing evidence on the use of nonpharmacologic, nonherbal interventions to manage bothersome vasomotor symptoms in perimenopausal and postmenopausal women. Systematic review registration: PROSPERO CRD42016029335

Original languageEnglish (US)
Article number56
JournalSystematic Reviews
Volume5
Issue number1
DOIs
StatePublished - Apr 7 2016
Externally publishedYes

Keywords

  • Menopause
  • Nonpharmacologic therapy
  • Umbrella review
  • Vasomotor symptoms

ASJC Scopus subject areas

  • Medicine (miscellaneous)

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    Goldstein, K. M., McDuffie, J. R., Shepherd-Banigan, M., Befus, D., Coeytaux, R. R., Van Noord, M. G., Goode, A. P., Masilamani, V., Adam, S., Nagi, A., & Williams, J. W. (2016). Nonpharmacologic, nonherbal management of menopause-associated vasomotor symptoms: An umbrella systematic review (protocol). Systematic Reviews, 5(1), [56]. https://doi.org/10.1186/s13643-016-0232-6