Noninfectious canine arthritis

rheumatoid arthritis

Niels C Pedersen, R. C. Pool, J. J. Castles, K. Weisner

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Chronic unremitting, generally symmetric, erosive polyarthritis was studied in 8 dogs. The disease had clinical, serologic, radiographic, and pathologic changes similar to those of rheumatoid arthritis of man. The condition occurred mainly in smaller breeds of dogs, with time of onset from 8 months to 8 years of age. Characteristic radiographic changes were seen in the joints several weeks to several months after the appearance of the initial lameness. Synovial fluid contained an increased number of neutrophils, and synovial fluid and synovial tissues were sterile for anaerobic and aerobic bacteria, mycoplasma, chlamydia, and viruses. Corticosteroids were therapeutically ineffective in all of the cases; however, corticosteroids, cyclophosphamide, and azathioprine were effective when used in combination in several dogs.

Original languageEnglish (US)
Pages (from-to)295-303
Number of pages9
JournalJournal of the American Veterinary Medical Association
Volume169
Issue number3
StatePublished - 1976

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synovial fluid
rheumatoid arthritis
arthritis
adrenal cortex hormones
Arthritis
Canidae
Rheumatoid Arthritis
Synovial Fluid
Dogs
Chlamydia
cyclophosphamide
dogs
Adrenal Cortex Hormones
Mycoplasma
dog breeds
joints (animal)
lameness
neutrophils
Aerobic Bacteria
Anaerobic Bacteria

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Noninfectious canine arthritis : rheumatoid arthritis. / Pedersen, Niels C; Pool, R. C.; Castles, J. J.; Weisner, K.

In: Journal of the American Veterinary Medical Association, Vol. 169, No. 3, 1976, p. 295-303.

Research output: Contribution to journalArticle

Pedersen, Niels C ; Pool, R. C. ; Castles, J. J. ; Weisner, K. / Noninfectious canine arthritis : rheumatoid arthritis. In: Journal of the American Veterinary Medical Association. 1976 ; Vol. 169, No. 3. pp. 295-303.
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