Abstract
Chronic unremitting, generally symmetric, erosive polyarthritis was studied in 8 dogs. The disease had clinical, serologic, radiographic, and pathologic changes similar to those of rheumatoid arthritis of man. The condition occurred mainly in smaller breeds of dogs, with time of onset from 8 months to 8 years of age. Characteristic radiographic changes were seen in the joints several weeks to several months after the appearance of the initial lameness. Synovial fluid contained an increased number of neutrophils, and synovial fluid and synovial tissues were sterile for anaerobic and aerobic bacteria, mycoplasma, chlamydia, and viruses. Corticosteroids were therapeutically ineffective in all of the cases; however, corticosteroids, cyclophosphamide, and azathioprine were effective when used in combination in several dogs.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 295-303 |
| Number of pages | 9 |
| Journal | Journal of the American Veterinary Medical Association |
| Volume | 169 |
| Issue number | 3 |
| State | Published - 1976 |
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ASJC Scopus subject areas
- veterinary(all)
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Noninfectious canine arthritis : rheumatoid arthritis. / Pedersen, Niels C; Pool, R. C.; Castles, J. J.; Weisner, K.
In: Journal of the American Veterinary Medical Association, Vol. 169, No. 3, 1976, p. 295-303.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Noninfectious canine arthritis
T2 - rheumatoid arthritis
AU - Pedersen, Niels C
AU - Pool, R. C.
AU - Castles, J. J.
AU - Weisner, K.
PY - 1976
Y1 - 1976
N2 - Chronic unremitting, generally symmetric, erosive polyarthritis was studied in 8 dogs. The disease had clinical, serologic, radiographic, and pathologic changes similar to those of rheumatoid arthritis of man. The condition occurred mainly in smaller breeds of dogs, with time of onset from 8 months to 8 years of age. Characteristic radiographic changes were seen in the joints several weeks to several months after the appearance of the initial lameness. Synovial fluid contained an increased number of neutrophils, and synovial fluid and synovial tissues were sterile for anaerobic and aerobic bacteria, mycoplasma, chlamydia, and viruses. Corticosteroids were therapeutically ineffective in all of the cases; however, corticosteroids, cyclophosphamide, and azathioprine were effective when used in combination in several dogs.
AB - Chronic unremitting, generally symmetric, erosive polyarthritis was studied in 8 dogs. The disease had clinical, serologic, radiographic, and pathologic changes similar to those of rheumatoid arthritis of man. The condition occurred mainly in smaller breeds of dogs, with time of onset from 8 months to 8 years of age. Characteristic radiographic changes were seen in the joints several weeks to several months after the appearance of the initial lameness. Synovial fluid contained an increased number of neutrophils, and synovial fluid and synovial tissues were sterile for anaerobic and aerobic bacteria, mycoplasma, chlamydia, and viruses. Corticosteroids were therapeutically ineffective in all of the cases; however, corticosteroids, cyclophosphamide, and azathioprine were effective when used in combination in several dogs.
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UR - http://www.scopus.com/inward/citedby.url?scp=0017170186&partnerID=8YFLogxK
M3 - Article
VL - 169
SP - 295
EP - 303
JO - Journal of the American Veterinary Medical Association
JF - Journal of the American Veterinary Medical Association
SN - 0003-1488
IS - 3
ER -