Noncoding RNAs in Cardiac Hypertrophy and Heart Failure

Peilei Lu, Fan Ding, Yang Kevin Xiang, Liying Hao, Meimi Zhao

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Heart failure is a major global health concern. Noncoding RNAs (ncRNAs) are involved in physiological processes and in the pathogenesis of various diseases, including heart failure. ncRNAs have emerged as critical components of transcriptional regulatory pathways that govern cardiac development, stress response, signaling, and remodeling in cardiac pathology. Recently, studies of ncRNAs in cardiovascular disease have achieved significant development. Here, we discuss the roles of ncRNAs, including microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs) that modulate the cardiac hypertrophy and heart failure.

Original languageEnglish (US)
Article number777
JournalCells
Volume11
Issue number5
DOIs
StatePublished - Mar 1 2022

Keywords

  • Cardiac hypertrophy
  • Heart failure
  • Noncoding RNAs

ASJC Scopus subject areas

  • Medicine(all)

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