Non-myelinated vagal lung receptors and their reflex effects on respiration in rabbits

Diana Trenchard, N. J W Russell, Helen E Raybould

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

The response characteristics of non-myelinated vagal lung receptors have been studied in the anaesthetized rabbit. The results indicate that the behaviour of these endings strongly resembles those found in cats and dogs and that they can be classified into 'pulmonary', 'bronchial' and 'pulmonary- bronchial' groups depending on their accessibility from either circulation. Experiments involving pericardial block with local anaesthetic to exclude responses from cardiac receptors and the use of sodium dithionite as a novel stimulus to 'pulmonary' ending alone, have shown that the predominant effect of these endings in the anaesthetized rabbit is to increae respiratory frequency. Reflex responses from 'bronchial' endings similar provided sufficient amount of the activating chemical was given.

Original languageEnglish (US)
Pages (from-to)63-79
Number of pages17
JournalRespiration Physiology
Volume55
Issue number1
DOIs
StatePublished - 1984
Externally publishedYes

Keywords

  • Bronchus
  • Heart
  • Lung
  • Pulmonary receptors
  • Receptors
  • Sodium dithionite
  • Vagus nerve
  • Ventilation

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine

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