Non-invasive antidromic neurostimulation: A simple effective method for improving bladder storage

I. K. Walsh, T. Thompson, W. G G Loughridge, S. R. Johnston, P. F. Keane, Anthony R Stone

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Patients with intractably diminished bladder storage function are encountered frequently by neurourologists, occasionally requiring reconstructive surgery for appropriate resolution. Although sacral neuromodulation is a recognized effective therapeutic modality, present techniques are technically demanding, invasive, and expensive. This study investigated the effect of non-invasive third sacral nerve (S3) stimulation on bladder activity during filling cystometry. One hundred forty-six patients underwent standard urodynamic filling cystometry that was then immmediately repeated. Patients in the study group (n = 74) received antidromic transcutaneous sacral neurostimulation during the second fill and the control group (n = 72) underwent a second fill without neurostimulation. A statistically significant increase in bladder storage capacity without a corresponding rise in detrusor pressure was observed in the neurostimulated patients. This improvement in functional capacity is an encouraging finding that further supports the use of this non-invasive treatment modality in clinical practice.

Original languageEnglish (US)
Pages (from-to)73-84
Number of pages12
JournalNeurourology and Urodynamics
Issue number1
StatePublished - 2001


  • Cystometry
  • Neuromodulation
  • Neurostimulation
  • Sacral nerve

ASJC Scopus subject areas

  • Clinical Neurology
  • Nephrology
  • Urology


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