Nodular immunocyte-derived (AL) amyloidosis in the trachea of a dog

M. Faulkner Besancon, Brian A. Stacy, Andrew E. Kyles, Peter F Moore, William Vernau, Sean D. Smarick, Liberty A. Rasor

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

A 7-year-old castrated male Miniature Schnauzer was examined because of labored breathing and episodes of respiratory distress that progressed to collapse. On cervical radiographs, a focal soft tissue mass in the caudal cervical portion of the trachea was observed, and during tracheoscopy, a 1 X 1 cm, pedunculated, multinodular, pink, intraluminal mass extending from the dorsal tracheal membrane and obstructing approximately 80% of the tracheal lumen was seen. Tracheal resection and anastomosis was performed to remove the mass, and the dog recovered without complications. On histologic examination, the mass consisted of a large accumulation of homogeneous, faintly fibrillar eosinophilic material admixed with a predominantly plasma cell infiltrate; examination of sections stained with thioflavin T and Congo red stain confirmed that the eosinophilic material was amyloid. A diagnosis of nodular, immunocyte-derived (AL) amyloidosis was made. Seventeen months after surgery, the dog had a relapse of respiratory distress because of an extramedullary plasmacytoma involving the trachea.

Original languageEnglish (US)
Pages (from-to)1302-1306+1280
JournalJournal of the American Veterinary Medical Association
Volume224
Issue number8
DOIs
StatePublished - Apr 15 2004

ASJC Scopus subject areas

  • veterinary(all)

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