Nocardia cyriacigeorgica as the causative agent of mandibular osteomyelitis (lumpy jaw) in a cat

Esteban Soto Martinez, Maziel Arauz, Christa Ann Gallagher, Oscar Illanes

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

An unusual case of osteomyelitis caused by Nocardia cyriacigeorgica infection and resulting in mandibular osteomyelitis and cellulitis (lumpy jaw) is described in a young cat. A 1-cm hard nodular mass was an incidental finding in the right mandible of a 14-month-old cat during routine physical examination. The lesion was fast growing, reaching up to 6 cm in its largest dimension over a 5-week period. A core biopsy of the affected mandible revealed foci of osteolysis, woven bone formation, and a few large clusters of filamentous bacteria surrounded by fine eosinophilic amorphous material bordered by neutrophils, plasma cells, macrophages, and occasional multinucleated giant cells. Pure cultures of acid-fast variable, Gram-positive filamentous bacteria were recovered on blood and chocolate agar plates at 48-hr postinoculation. On amplification and sequencing of the 16S ribosomal RNA and 65-kDa heat shock protein genes, the microorganisms were identified as N. cyriacigeorgica, within the actinomycetes.

Original languageEnglish (US)
Pages (from-to)580-584
Number of pages5
JournalJournal of Veterinary Diagnostic Investigation
Volume26
Issue number4
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Nocardia
osteomyelitis
mandible (bone)
Osteomyelitis
Jaw
Mandible
jaws
Cats
cats
Nocardia Infections
16S Ribosomal RNA
cellulitis
Osteolysis
Incidental Findings
Cellulitis
Actinobacteria
plasma cells
bacteria
chocolate
Gram-Positive Bacteria

Keywords

  • Cats
  • lumpy jaw
  • mandibular osteomyelitis
  • Nocardia

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Nocardia cyriacigeorgica as the causative agent of mandibular osteomyelitis (lumpy jaw) in a cat. / Soto Martinez, Esteban; Arauz, Maziel; Gallagher, Christa Ann; Illanes, Oscar.

In: Journal of Veterinary Diagnostic Investigation, Vol. 26, No. 4, 2014, p. 580-584.

Research output: Contribution to journalArticle

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