Abstract
The effects of (-) nicotine hydrogen tartrate (NHT) were examined on several cell types in the CA1 region of rat hippocampus. The results indicate that nicotine may have a preferential net inhibitory effect on basket cells and an excitatory effect on oriens/alveus interneurons. The resultant effects of nicotine on pyramidal cells may thus be a product of complex local circuit interactions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 287-290 |
| Number of pages | 4 |
| Journal | Brain Research |
| Volume | 540 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Feb 1 1991 |
| Externally published | Yes |
Keywords
- Acetylcholine
- CA1
- Interneuron
- Nicotine
- Rat hippocampus
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)
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Cite this
Reece, L. J., & Schwartzkroin, P. A. (1991). Nicotine exerts differential effects on different CA1 hippocampal cell types. Brain Research, 540(1-2), 287-290. https://doi.org/10.1016/0006-8993(91)90520-6