Nicotine exerts differential effects on different CA1 hippocampal cell types

Laura J. Reece; Philip A Schwartzkroin

doi:10.1016/0006-8993(91)90520-6

Nicotine exerts differential effects on different CA1 hippocampal cell types

Laura J. Reece, Philip A Schwartzkroin

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The effects of (-) nicotine hydrogen tartrate (NHT) were examined on several cell types in the CA1 region of rat hippocampus. The results indicate that nicotine may have a preferential net inhibitory effect on basket cells and an excitatory effect on oriens/alveus interneurons. The resultant effects of nicotine on pyramidal cells may thus be a product of complex local circuit interactions.

Original language	English (US)
Pages (from-to)	287-290
Number of pages	4
Journal	Brain Research
Volume	540
Issue number	1-2
DOIs	https://doi.org/10.1016/0006-8993(91)90520-6
State	Published - Feb 1 1991
Externally published	Yes

Keywords

Acetylcholine
CA1
Interneuron
Nicotine
Rat hippocampus

ASJC Scopus subject areas

Developmental Biology
Molecular Biology
Clinical Neurology
Neuroscience(all)

Access to Document

10.1016/0006-8993(91)90520-6

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