Abstract
The effects of (-) nicotine hydrogen tartrate (NHT) were examined on several cell types in the CA1 region of rat hippocampus. The results indicate that nicotine may have a preferential net inhibitory effect on basket cells and an excitatory effect on oriens/alveus interneurons. The resultant effects of nicotine on pyramidal cells may thus be a product of complex local circuit interactions.
Original language | English (US) |
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Pages (from-to) | 287-290 |
Number of pages | 4 |
Journal | Brain Research |
Volume | 540 |
Issue number | 1-2 |
DOIs | |
State | Published - Feb 1 1991 |
Externally published | Yes |
Keywords
- Acetylcholine
- CA1
- Interneuron
- Nicotine
- Rat hippocampus
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)