Abstract
Millions of patients are evaluated every year in the emergency department (ED) for bacterial infections. Emergency physicians often diagnose and prescribe initial antibiotic therapy for a variety of bacterial infections, ranging from simple urinary tract infections to severe sepsis. In life-threatening infections, inappropriate choice of initial antibiotic has been shown to increase morbidity and mortality. As such, initiation of appropriate antibiotic therapy on the part of the emergency physician is critical. Increasing rates of antibiotic resistance, drug allergies, and antibiotic shortages further complicates the choice of antibiotics. Patients may have a history of prior resistant infections or culture data indicating that common first-line antibiotics used in the ED may be ineffective. In recent years, there have been several new antibiotic approvals as well as renewed interest in second and third line antibiotics because of the aforementioned concerns. In addition, several newly approved antibiotics have the advantage of being administered once weekly or even as a single infusion, which has the potential to decrease hospitalizations and healthcare costs. This article reviews newly approved antibiotics and antibiotics used to treat resistant infections with a focus on implications for emergency medicine.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 154-158 |
| Number of pages | 5 |
| Journal | American Journal of Emergency Medicine |
| Volume | 35 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2017 |
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ASJC Scopus subject areas
- Emergency Medicine
Cite this
Newly approved antibiotics and antibiotics reserved for resistant infections : Implications for emergency medicine. / Mazer-Amirshahi, Maryann; Pourmand, Ali; May, Larissa S.
In: American Journal of Emergency Medicine, Vol. 35, No. 1, 01.01.2017, p. 154-158.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Newly approved antibiotics and antibiotics reserved for resistant infections
T2 - Implications for emergency medicine
AU - Mazer-Amirshahi, Maryann
AU - Pourmand, Ali
AU - May, Larissa S
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Millions of patients are evaluated every year in the emergency department (ED) for bacterial infections. Emergency physicians often diagnose and prescribe initial antibiotic therapy for a variety of bacterial infections, ranging from simple urinary tract infections to severe sepsis. In life-threatening infections, inappropriate choice of initial antibiotic has been shown to increase morbidity and mortality. As such, initiation of appropriate antibiotic therapy on the part of the emergency physician is critical. Increasing rates of antibiotic resistance, drug allergies, and antibiotic shortages further complicates the choice of antibiotics. Patients may have a history of prior resistant infections or culture data indicating that common first-line antibiotics used in the ED may be ineffective. In recent years, there have been several new antibiotic approvals as well as renewed interest in second and third line antibiotics because of the aforementioned concerns. In addition, several newly approved antibiotics have the advantage of being administered once weekly or even as a single infusion, which has the potential to decrease hospitalizations and healthcare costs. This article reviews newly approved antibiotics and antibiotics used to treat resistant infections with a focus on implications for emergency medicine.
AB - Millions of patients are evaluated every year in the emergency department (ED) for bacterial infections. Emergency physicians often diagnose and prescribe initial antibiotic therapy for a variety of bacterial infections, ranging from simple urinary tract infections to severe sepsis. In life-threatening infections, inappropriate choice of initial antibiotic has been shown to increase morbidity and mortality. As such, initiation of appropriate antibiotic therapy on the part of the emergency physician is critical. Increasing rates of antibiotic resistance, drug allergies, and antibiotic shortages further complicates the choice of antibiotics. Patients may have a history of prior resistant infections or culture data indicating that common first-line antibiotics used in the ED may be ineffective. In recent years, there have been several new antibiotic approvals as well as renewed interest in second and third line antibiotics because of the aforementioned concerns. In addition, several newly approved antibiotics have the advantage of being administered once weekly or even as a single infusion, which has the potential to decrease hospitalizations and healthcare costs. This article reviews newly approved antibiotics and antibiotics used to treat resistant infections with a focus on implications for emergency medicine.
UR - http://www.scopus.com/inward/record.url?scp=85006036919&partnerID=8YFLogxK
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U2 - 10.1016/j.ajem.2016.10.034
DO - 10.1016/j.ajem.2016.10.034
M3 - Review article
C2 - 28029487
AN - SCOPUS:85006036919
VL - 35
SP - 154
EP - 158
JO - American Journal of Emergency Medicine
JF - American Journal of Emergency Medicine
SN - 0735-6757
IS - 1
ER -