New synthetic method for benzofurans from 2-(cyanomethyl)phenyl derivatives

Hee Jun Kim, Jai Seo, Min Hyung Lee, Dong Seok Shin, Hyeong Baik Kim, Hyeongjin Cho, Byoung Se Lee, Dae Yoon Chi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A convenient and mild synthetic method of synthesizing benzofuran from various 2-(cyanomethyl)phenyl carbonyl compounds under reduced oxygen conditions is reported. Nine C-2 substituted benzofurans were synthesized at 52-89%.

Original languageEnglish (US)
Pages (from-to)3942-3947
Number of pages6
JournalTetrahedron
Volume68
Issue number21
DOIs
StatePublished - May 27 2012
Externally publishedYes

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Benzofurans
Carbonyl compounds
Oxygen
Derivatives
benzofuran

Keywords

  • Benzofuran
  • Benzyl cyanide
  • C2-substituted benzofuran
  • C3-carboxylated benzofuran
  • Intramolecular cyclization

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Kim, H. J., Seo, J., Lee, M. H., Shin, D. S., Kim, H. B., Cho, H., ... Chi, D. Y. (2012). New synthetic method for benzofurans from 2-(cyanomethyl)phenyl derivatives. Tetrahedron, 68(21), 3942-3947. https://doi.org/10.1016/j.tet.2012.03.088

New synthetic method for benzofurans from 2-(cyanomethyl)phenyl derivatives. / Kim, Hee Jun; Seo, Jai; Lee, Min Hyung; Shin, Dong Seok; Kim, Hyeong Baik; Cho, Hyeongjin; Lee, Byoung Se; Chi, Dae Yoon.

In: Tetrahedron, Vol. 68, No. 21, 27.05.2012, p. 3942-3947.

Research output: Contribution to journalArticle

Kim, HJ, Seo, J, Lee, MH, Shin, DS, Kim, HB, Cho, H, Lee, BS & Chi, DY 2012, 'New synthetic method for benzofurans from 2-(cyanomethyl)phenyl derivatives', Tetrahedron, vol. 68, no. 21, pp. 3942-3947. https://doi.org/10.1016/j.tet.2012.03.088
Kim, Hee Jun ; Seo, Jai ; Lee, Min Hyung ; Shin, Dong Seok ; Kim, Hyeong Baik ; Cho, Hyeongjin ; Lee, Byoung Se ; Chi, Dae Yoon. / New synthetic method for benzofurans from 2-(cyanomethyl)phenyl derivatives. In: Tetrahedron. 2012 ; Vol. 68, No. 21. pp. 3942-3947.
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