Abstract
We present three new radiofrequency probes for nuclear magnetic resonance (NMR) research with perfused rabbit hearts at different maturational ages. The objective of the double-tunable, cylindrical-window probe design was to achieve a highly homogeneous magnetic field throughout the 16, 25 or 30 mm diameter usable volume for consistency of comparison of measurements obtained from neonate, immature and adult rabbit hearts, respectively. This probe design tunes to 23-Sodium for rapid shimming and then, to 31-Phosphorus for measurements of pH and high energy phosphate metabolites. All three probes yielded excellent signal-to-noise ratios and radiofrequency operating characteristics. We introduce these new probes here in the context of a brief review of other state-of-the-art designs for in vitro and in vivo cardiovascular research.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 45-59 |
| Number of pages | 15 |
| Journal | Biomaterials, Artificial Cells, and Artificial Organs |
| Volume | 17 |
| Issue number | 1 |
| State | Published - 1989 |
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ASJC Scopus subject areas
- Medicine(all)
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New NMR probe designs for neonatal, immature and adult heart research. With a brief review. / Kost, Gerald J; Anderson, S. E.; Conboy, C. B.
In: Biomaterials, Artificial Cells, and Artificial Organs, Vol. 17, No. 1, 1989, p. 45-59.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New NMR probe designs for neonatal, immature and adult heart research. With a brief review
AU - Kost, Gerald J
AU - Anderson, S. E.
AU - Conboy, C. B.
PY - 1989
Y1 - 1989
N2 - We present three new radiofrequency probes for nuclear magnetic resonance (NMR) research with perfused rabbit hearts at different maturational ages. The objective of the double-tunable, cylindrical-window probe design was to achieve a highly homogeneous magnetic field throughout the 16, 25 or 30 mm diameter usable volume for consistency of comparison of measurements obtained from neonate, immature and adult rabbit hearts, respectively. This probe design tunes to 23-Sodium for rapid shimming and then, to 31-Phosphorus for measurements of pH and high energy phosphate metabolites. All three probes yielded excellent signal-to-noise ratios and radiofrequency operating characteristics. We introduce these new probes here in the context of a brief review of other state-of-the-art designs for in vitro and in vivo cardiovascular research.
AB - We present three new radiofrequency probes for nuclear magnetic resonance (NMR) research with perfused rabbit hearts at different maturational ages. The objective of the double-tunable, cylindrical-window probe design was to achieve a highly homogeneous magnetic field throughout the 16, 25 or 30 mm diameter usable volume for consistency of comparison of measurements obtained from neonate, immature and adult rabbit hearts, respectively. This probe design tunes to 23-Sodium for rapid shimming and then, to 31-Phosphorus for measurements of pH and high energy phosphate metabolites. All three probes yielded excellent signal-to-noise ratios and radiofrequency operating characteristics. We introduce these new probes here in the context of a brief review of other state-of-the-art designs for in vitro and in vivo cardiovascular research.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024319132&partnerID=8YFLogxK
M3 - Article
VL - 17
SP - 45
EP - 59
JO - Artificial Cells, Nanomedicine and Biotechnology
JF - Artificial Cells, Nanomedicine and Biotechnology
SN - 2169-1401
IS - 1
ER -