The autoantibodies characteristic of the disease react against mitochondrial enzymes essential to the function of all body cells, yet the disease is highly focused on only one tissue: the epithelial lining of intrahepatic bile ductules. The explanation may lie in tissue-specific cell- surface expression of a triggering antigen.
|Original language||English (US)|
|Number of pages||8|
|State||Published - 1995|
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