Abstract
Background: Classical zinc finger proteins are extremely abundant and interact with DNA using a well defined recognition code. Results: We solved the structure of ZNF217 bound to its cognate DNA. Conclusion: ZNF217 presents a unique DNA interaction pattern including a new type of protein-DNA contact. Significance: This study deepens our understanding of DNA recognition by classical zinc fingers.
Original language | English (US) |
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Pages (from-to) | 10616-10627 |
Number of pages | 12 |
Journal | Journal of Biological Chemistry |
Volume | 288 |
Issue number | 15 |
DOIs | |
State | Published - Apr 12 2013 |
ASJC Scopus subject areas
- Biochemistry
- Cell Biology
- Molecular Biology