New evolutionary frontiers from unusual virus genomes

Christopher Desjardins, Jonathan A Eisen, Vishvanath Nene

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


The sequences of two giant viral genomes, Mimivirus and a polydnavirus, have recently been published. Mimivirus has the largest known viral genome and encodes an unprecedented number of proteins, whereas the polydnavirus genome has an extremely low coding density and does not encode DNA-replication proteins. These and other unusual features challenge the way we view the evolution and definition of viruses.

Original languageEnglish (US)
Article number212
JournalGenome Biology
Issue number3
StatePublished - 2005
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Cell Biology
  • Ecology, Evolution, Behavior and Systematics


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