New directions in neurotransmitter action: dopamine provides some important clues

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

New discoveries in the retina have provided a unique view of how dopamine (DA) operates as a neurotransmitter. In certain fish retinae, DA, acting through D-1 receptors linked to adenylate cyclase, serves to uncouple electrical synapses between horizontal cells. In other fish species, DA induces the physical retraction of cones and the elongation of rods by an action on D-2 receptors localized to the photoreceptor membrane. These novel actions of DA provide important clues for investigating the physiological role of DA elsewhere in the nervous system.

Original languageEnglish (US)
Pages (from-to)200-205
Number of pages6
JournalTrends in Neurosciences
Volume10
Issue number5
DOIs
StatePublished - 1987
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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