New directions for studying cognitive decline in old monkeys

Peter R. Rapp; Mary T. Kansky; Jeffrey A Roberts; Howard Eichenbaum

doi:10.1006/smns.1994.1048

New directions for studying cognitive decline in old monkeys

Peter R. Rapp, Mary T. Kansky, Jeffrey A Roberts, Howard Eichenbaum

Medicine and Epidemiology

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A cognitive neuroscience perspective provides a valuable framework for organizing data on the behavioral consequences of aging in nonhuman primates. Growing evidence suggests that working memory processes known to depend on the functional integrity of the prefrontal cortex are particularly susceptible to aging in the monkey. By comparison, the status of memory supported by the hippocampus and related medial temporal lobe structures appears more variable across aged individuals. Combined with recent conceptual advances in the broader field of learning and memory research, these findings provide a solid foundation for developing new strategies to establish a complete neuropsychological account of cognitive aging in the monkey.

Original language	English (US)
Pages (from-to)	369-377
Number of pages	9
Journal	Seminars in Neuroscience
Volume	6
Issue number	6
DOIs	https://doi.org/10.1006/smns.1994.1048
State	Published - Dec 1994

Keywords

aging/learning/memory/monkey/neuropsychology

ASJC Scopus subject areas

Neuroscience(all)

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10.1006/smns.1994.1048

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AB - A cognitive neuroscience perspective provides a valuable framework for organizing data on the behavioral consequences of aging in nonhuman primates. Growing evidence suggests that working memory processes known to depend on the functional integrity of the prefrontal cortex are particularly susceptible to aging in the monkey. By comparison, the status of memory supported by the hippocampus and related medial temporal lobe structures appears more variable across aged individuals. Combined with recent conceptual advances in the broader field of learning and memory research, these findings provide a solid foundation for developing new strategies to establish a complete neuropsychological account of cognitive aging in the monkey.

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New directions for studying cognitive decline in old monkeys

Abstract

Keywords

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