Abstract
A cognitive neuroscience perspective provides a valuable framework for organizing data on the behavioral consequences of aging in nonhuman primates. Growing evidence suggests that working memory processes known to depend on the functional integrity of the prefrontal cortex are particularly susceptible to aging in the monkey. By comparison, the status of memory supported by the hippocampus and related medial temporal lobe structures appears more variable across aged individuals. Combined with recent conceptual advances in the broader field of learning and memory research, these findings provide a solid foundation for developing new strategies to establish a complete neuropsychological account of cognitive aging in the monkey.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 369-377 |
| Number of pages | 9 |
| Journal | Seminars in Neuroscience |
| Volume | 6 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 1994 |
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Keywords
- aging/learning/memory/monkey/neuropsychology
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
New directions for studying cognitive decline in old monkeys. / Rapp, Peter R.; Kansky, Mary T.; Roberts, Jeffrey A; Eichenbaum, Howard.
In: Seminars in Neuroscience, Vol. 6, No. 6, 12.1994, p. 369-377.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New directions for studying cognitive decline in old monkeys
AU - Rapp, Peter R.
AU - Kansky, Mary T.
AU - Roberts, Jeffrey A
AU - Eichenbaum, Howard
PY - 1994/12
Y1 - 1994/12
N2 - A cognitive neuroscience perspective provides a valuable framework for organizing data on the behavioral consequences of aging in nonhuman primates. Growing evidence suggests that working memory processes known to depend on the functional integrity of the prefrontal cortex are particularly susceptible to aging in the monkey. By comparison, the status of memory supported by the hippocampus and related medial temporal lobe structures appears more variable across aged individuals. Combined with recent conceptual advances in the broader field of learning and memory research, these findings provide a solid foundation for developing new strategies to establish a complete neuropsychological account of cognitive aging in the monkey.
AB - A cognitive neuroscience perspective provides a valuable framework for organizing data on the behavioral consequences of aging in nonhuman primates. Growing evidence suggests that working memory processes known to depend on the functional integrity of the prefrontal cortex are particularly susceptible to aging in the monkey. By comparison, the status of memory supported by the hippocampus and related medial temporal lobe structures appears more variable across aged individuals. Combined with recent conceptual advances in the broader field of learning and memory research, these findings provide a solid foundation for developing new strategies to establish a complete neuropsychological account of cognitive aging in the monkey.
KW - aging/learning/memory/monkey/neuropsychology
UR - http://www.scopus.com/inward/record.url?scp=0028645507&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028645507&partnerID=8YFLogxK
U2 - 10.1006/smns.1994.1048
DO - 10.1006/smns.1994.1048
M3 - Article
VL - 6
SP - 369
EP - 377
JO - Seminars in the Neurosciences
JF - Seminars in the Neurosciences
SN - 1044-5765
IS - 6
ER -