New developments in eye models with retina tissue phantoms for ophthalmic optical coherence tomography

T. Scott Rowe, Robert Zawadzki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Citations (Scopus)

Abstract

We document our latest work in developing eye models with solid-state retinal tissue phantoms designed for demonstrating, validating and comparing ophthalmic Optical Coherence Tomography (OCT) instruments. Eye models with retina tissue phantoms can serve a variety of purposes, including demonstrating OCT functionality and performance in both the clinic and exhibit hall, validating retina layer thickness measurements from different commercial OCT instruments and as an aide for the R&D engineer and field service technician in the development and repair of instruments, respectively. The ideal eye model for OCT, the optical cross-sectional imaging modality, would have a volumetric morphology and scattering and absorption properties similar to that of normal human retina. These include a multi-layered structure of equivalent thickness to nominal human retina layers, a foveal pit that can be used to orient the image, and a RPE/OS and choroid like layers to demonstrate the depth penetration of the OCT system. A solid state tissue phantom relieves the user of constant cleaning and maintenance associated with the more common water bath model eyes. Novel processes12 have been developed to create retinal layers model that closely mimic the reflectance and scattering coefficients of the real layers of the retina, as imaged by spectral bandwidth of OCT.

Original languageEnglish (US)
Title of host publicationOptical Diagnostics and Sensing XII
Subtitle of host publicationToward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV
Volume8229
DOIs
StatePublished - Mar 19 2012
EventOptical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV - San Francisco, CA, United States
Duration: Jan 21 2012Jan 26 2012

Other

OtherOptical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV
CountryUnited States
CitySan Francisco, CA
Period1/21/121/26/12

Fingerprint

retina
Optical tomography
Optical Coherence Tomography
Retina
tomography
Tissue
Scattering
solid state
Thickness measurement
Choroid
scattering coefficients
Baths
cleaning
engineers
maintenance
baths
Cleaning
Repair
penetration
Maintenance

Keywords

  • Artificial eye
  • Eye model
  • OCT
  • Ophthalmic eye model
  • Optical coherence tomography
  • Retina phantom
  • Target eye
  • Test eye
  • Tissue phantom

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Scott Rowe, T., & Zawadzki, R. (2012). New developments in eye models with retina tissue phantoms for ophthalmic optical coherence tomography. In Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV (Vol. 8229). [822913] https://doi.org/10.1117/12.905499

New developments in eye models with retina tissue phantoms for ophthalmic optical coherence tomography. / Scott Rowe, T.; Zawadzki, Robert.

Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV. Vol. 8229 2012. 822913.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Scott Rowe, T & Zawadzki, R 2012, New developments in eye models with retina tissue phantoms for ophthalmic optical coherence tomography. in Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV. vol. 8229, 822913, Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV, San Francisco, CA, United States, 1/21/12. https://doi.org/10.1117/12.905499
Scott Rowe T, Zawadzki R. New developments in eye models with retina tissue phantoms for ophthalmic optical coherence tomography. In Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV. Vol. 8229. 2012. 822913 https://doi.org/10.1117/12.905499
Scott Rowe, T. ; Zawadzki, Robert. / New developments in eye models with retina tissue phantoms for ophthalmic optical coherence tomography. Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue IV. Vol. 8229 2012.
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