New approaches in the pharmacotherapy of posttraumatic stress disorder

J. M. Silver, D. P. Sandberg, Robert E Hales

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Posttraumatic stress disorder (PTSD) may develop after exposure to severe stress, such as combat, accidents, assaults, and natural disasters. Pharmacotherapy can be a useful adjunct in the comprehensive treatment of these patients. The presence of comorbid conditions, including depression, panic disorder, substance abuse, and traumatic brain injury, should be carefully evaluated. Symptoms of PTSD that are associated with central nervous system hyperarousal or reexperiencing of the traumatic event appear to be the most responsive to pharmacotherapy. Social withdrawal and dulled responsiveness have not been shown to be alleviated through standard pharmacologic interventions. A therapeutic strategy is proposed that is based on the patient's symptoms and initial response to medication.

Original languageEnglish (US)
Pages (from-to)33-38
Number of pages6
JournalJournal of Clinical Psychiatry
Volume51
Issue number10 SUPPL.
StatePublished - 1990
Externally publishedYes

Fingerprint

Post-Traumatic Stress Disorders
Drug Therapy
Panic Disorder
Disasters
Substance-Related Disorders
Accidents
Central Nervous System
Depression
Therapeutics
Traumatic Brain Injury

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

New approaches in the pharmacotherapy of posttraumatic stress disorder. / Silver, J. M.; Sandberg, D. P.; Hales, Robert E.

In: Journal of Clinical Psychiatry, Vol. 51, No. 10 SUPPL., 1990, p. 33-38.

Research output: Contribution to journalArticle

Silver, J. M. ; Sandberg, D. P. ; Hales, Robert E. / New approaches in the pharmacotherapy of posttraumatic stress disorder. In: Journal of Clinical Psychiatry. 1990 ; Vol. 51, No. 10 SUPPL. pp. 33-38.
@article{78886ae3fa4e41fbb4018d85c70fe774,
title = "New approaches in the pharmacotherapy of posttraumatic stress disorder",
abstract = "Posttraumatic stress disorder (PTSD) may develop after exposure to severe stress, such as combat, accidents, assaults, and natural disasters. Pharmacotherapy can be a useful adjunct in the comprehensive treatment of these patients. The presence of comorbid conditions, including depression, panic disorder, substance abuse, and traumatic brain injury, should be carefully evaluated. Symptoms of PTSD that are associated with central nervous system hyperarousal or reexperiencing of the traumatic event appear to be the most responsive to pharmacotherapy. Social withdrawal and dulled responsiveness have not been shown to be alleviated through standard pharmacologic interventions. A therapeutic strategy is proposed that is based on the patient's symptoms and initial response to medication.",
author = "Silver, {J. M.} and Sandberg, {D. P.} and Hales, {Robert E}",
year = "1990",
language = "English (US)",
volume = "51",
pages = "33--38",
journal = "Journal of Clinical Psychiatry",
issn = "0160-6689",
publisher = "Physicians Postgraduate Press Inc.",
number = "10 SUPPL.",

}

TY - JOUR

T1 - New approaches in the pharmacotherapy of posttraumatic stress disorder

AU - Silver, J. M.

AU - Sandberg, D. P.

AU - Hales, Robert E

PY - 1990

Y1 - 1990

N2 - Posttraumatic stress disorder (PTSD) may develop after exposure to severe stress, such as combat, accidents, assaults, and natural disasters. Pharmacotherapy can be a useful adjunct in the comprehensive treatment of these patients. The presence of comorbid conditions, including depression, panic disorder, substance abuse, and traumatic brain injury, should be carefully evaluated. Symptoms of PTSD that are associated with central nervous system hyperarousal or reexperiencing of the traumatic event appear to be the most responsive to pharmacotherapy. Social withdrawal and dulled responsiveness have not been shown to be alleviated through standard pharmacologic interventions. A therapeutic strategy is proposed that is based on the patient's symptoms and initial response to medication.

AB - Posttraumatic stress disorder (PTSD) may develop after exposure to severe stress, such as combat, accidents, assaults, and natural disasters. Pharmacotherapy can be a useful adjunct in the comprehensive treatment of these patients. The presence of comorbid conditions, including depression, panic disorder, substance abuse, and traumatic brain injury, should be carefully evaluated. Symptoms of PTSD that are associated with central nervous system hyperarousal or reexperiencing of the traumatic event appear to be the most responsive to pharmacotherapy. Social withdrawal and dulled responsiveness have not been shown to be alleviated through standard pharmacologic interventions. A therapeutic strategy is proposed that is based on the patient's symptoms and initial response to medication.

UR - http://www.scopus.com/inward/record.url?scp=0025086439&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025086439&partnerID=8YFLogxK

M3 - Article

C2 - 2120203

AN - SCOPUS:0025086439

VL - 51

SP - 33

EP - 38

JO - Journal of Clinical Psychiatry

JF - Journal of Clinical Psychiatry

SN - 0160-6689

IS - 10 SUPPL.

ER -