Abstract
A new theory is presented to describe the detailed structure of the osmotic gradients and the flow across the endothelial surface glycocalyx, the inter-endothelial cleft, and the exit region downstream of the cleft exit. The nonlinear coupling of the local fluid flow to the local plasma protein concentration is examined. The primary gradient in osmotic force is felt across the surface layer of matrix. The model shows that there is an unrecognized large asymmetry in the fluid flow pattern on each side of the junction strand and the water enters the cleft nearly uniformly along its length despite the widely separated discrete breaks in the junction strand.
| Original language | English (US) |
|---|---|
| Title of host publication | American Society of Mechanical Engineers, Bioengineering Division (Publication) BED |
| Editors | W.S. Chang, A. Gopinath, S.S. Sadhal, E.H. Trinh, C.J. Kim, al et al |
| Place of Publication | Fairfield, NJ, United States |
| Publisher | ASME |
| Pages | 73 |
| Number of pages | 1 |
| Volume | 36 |
| Publication status | Published - 1997 |
| Externally published | Yes |
| Event | Proceedings of the 1997 ASME International Mechanical Engineering Congress and Exposition - Dallas, TX, USA Duration: Nov 16 1997 → Nov 21 1997 |
Other
| Other | Proceedings of the 1997 ASME International Mechanical Engineering Congress and Exposition |
|---|---|
| City | Dallas, TX, USA |
| Period | 11/16/97 → 11/21/97 |
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ASJC Scopus subject areas
- Engineering(all)
Cite this
Hu, X., Curry, F., & Weinbaum, S. (1997). New approach to understanding Starling's law at the microstructural level. In W. S. Chang, A. Gopinath, S. S. Sadhal, E. H. Trinh, C. J. Kim, & A. et al (Eds.), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 36, pp. 73). Fairfield, NJ, United States: ASME.