Abstract
We previously demonstrated that the area encompassing residues 147-162 of the envelope protein of simian retrovirus serotype-1 (SRV-1) is the target for rhesus anti-SRV-1 neutralizing antibodies. A peptide representing amino acids 142-167 of envelope protein (gp70) is capable of inducing virus-neutralizing antibodies in mice. The virus receptor was immunoprecipitated from Raji cells using gp70 as the ligand. Antibodies to peptide 142-167 inhibit the immunoprecipitation, indicating that the receptor recognizes residues 142-167 of the viral envelope protein.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 218-221 |
| Number of pages | 4 |
| Journal | Journal of Medical Primatology |
| Volume | 20 |
| Issue number | 4 |
| State | Published - Jun 1991 |
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ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)
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Neutralization epitope in the envelope glycoprotein of simian retrovirus-1 (SRV-1) and identification of the virus receptor. / Torres, Jose V; Werner, L. L.; Malley, A.; Benjamin, E.
In: Journal of Medical Primatology, Vol. 20, No. 4, 06.1991, p. 218-221.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neutralization epitope in the envelope glycoprotein of simian retrovirus-1 (SRV-1) and identification of the virus receptor.
AU - Torres, Jose V
AU - Werner, L. L.
AU - Malley, A.
AU - Benjamin, E.
PY - 1991/6
Y1 - 1991/6
N2 - We previously demonstrated that the area encompassing residues 147-162 of the envelope protein of simian retrovirus serotype-1 (SRV-1) is the target for rhesus anti-SRV-1 neutralizing antibodies. A peptide representing amino acids 142-167 of envelope protein (gp70) is capable of inducing virus-neutralizing antibodies in mice. The virus receptor was immunoprecipitated from Raji cells using gp70 as the ligand. Antibodies to peptide 142-167 inhibit the immunoprecipitation, indicating that the receptor recognizes residues 142-167 of the viral envelope protein.
AB - We previously demonstrated that the area encompassing residues 147-162 of the envelope protein of simian retrovirus serotype-1 (SRV-1) is the target for rhesus anti-SRV-1 neutralizing antibodies. A peptide representing amino acids 142-167 of envelope protein (gp70) is capable of inducing virus-neutralizing antibodies in mice. The virus receptor was immunoprecipitated from Raji cells using gp70 as the ligand. Antibodies to peptide 142-167 inhibit the immunoprecipitation, indicating that the receptor recognizes residues 142-167 of the viral envelope protein.
UR - http://www.scopus.com/inward/record.url?scp=0026179362&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026179362&partnerID=8YFLogxK
M3 - Article
VL - 20
SP - 218
EP - 221
JO - Journal of Medical Primatology
JF - Journal of Medical Primatology
SN - 0047-2565
IS - 4
ER -