Abstract
We previously demonstrated that the area encompassing residues 147-162 of the envelope protein of simian retrovirus serotype-1 (SRV-1) is the target for rhesus anti-SRV-1 neutralizing antibodies. A peptide representing amino acids 142-167 of envelope protein (gp70) is capable of inducing virus-neutralizing antibodies in mice. The virus receptor was immunoprecipitated from Raji cells using gp70 as the ligand. Antibodies to peptide 142-167 inhibit the immunoprecipitation, indicating that the receptor recognizes residues 142-167 of the viral envelope protein.
Original language | English (US) |
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Pages (from-to) | 218-221 |
Number of pages | 4 |
Journal | Journal of Medical Primatology |
Volume | 20 |
Issue number | 4 |
State | Published - Jun 1991 |
ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)