Neutralization epitope in the envelope glycoprotein of simian retrovirus-1 (SRV-1) and identification of the virus receptor.

Jose V Torres, L. L. Werner, A. Malley, E. Benjamin

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We previously demonstrated that the area encompassing residues 147-162 of the envelope protein of simian retrovirus serotype-1 (SRV-1) is the target for rhesus anti-SRV-1 neutralizing antibodies. A peptide representing amino acids 142-167 of envelope protein (gp70) is capable of inducing virus-neutralizing antibodies in mice. The virus receptor was immunoprecipitated from Raji cells using gp70 as the ligand. Antibodies to peptide 142-167 inhibit the immunoprecipitation, indicating that the receptor recognizes residues 142-167 of the viral envelope protein.

Original languageEnglish (US)
Pages (from-to)218-221
Number of pages4
JournalJournal of Medical Primatology
Volume20
Issue number4
StatePublished - Jun 1991

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Mason-Pfizer monkey virus
Virus Receptors
Neutralizing Antibodies
neutralizing antibodies
neutralization
epitopes
glycoproteins
Epitopes
Glycoproteins
Retroviridae
peptides
Viral Envelope Proteins
Peptides
Immunoprecipitation
serotypes
Proteins
proteins
Ligands
Viruses
Amino Acids

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Neutralization epitope in the envelope glycoprotein of simian retrovirus-1 (SRV-1) and identification of the virus receptor. / Torres, Jose V; Werner, L. L.; Malley, A.; Benjamin, E.

In: Journal of Medical Primatology, Vol. 20, No. 4, 06.1991, p. 218-221.

Research output: Contribution to journalArticle

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