Neuroprotection during CPB: From mechanisms to interventions

John M. Murkin; Walter D Boyd; Su Ganapathy; Sandra J. Adams; Rhonda C. Peterson; Joanne Morgan; Peter Lok

Neuroprotection during CPB: From mechanisms to interventions

John M. Murkin, Walter D Boyd, Su Ganapathy, Sandra J. Adams, Rhonda C. Peterson, Joanne Morgan, Peter Lok

Research output: Contribution to journal › Article › peer-review

Abstract

The incidence and etiology of brain dysfunction after conventional coronary artery bypass surgery using cardiopulmonary bypass are reviewed. Stroke rates and incidences of cognitive dysfunction from various studies are considered. Mechanisms of injury including cerebral embolization as detected by transcranial Doppler and evidence for postoperative cerebral edema are discussed. Evidence for lower overall postoperative morbidity, and for a lower incidence of cognitive dysfunction specifically, after nonpump coronary revascularization is presented.

Original language	English (US)
Pages (from-to)	3-6
Number of pages	4
Journal	Seminars in Cardiothoracic and Vascular Anesthesia
Volume	6
Issue number	1
State	Published - 2002
Externally published	Yes

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

Cite this

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title = "Neuroprotection during CPB: From mechanisms to interventions",

abstract = "The incidence and etiology of brain dysfunction after conventional coronary artery bypass surgery using cardiopulmonary bypass are reviewed. Stroke rates and incidences of cognitive dysfunction from various studies are considered. Mechanisms of injury including cerebral embolization as detected by transcranial Doppler and evidence for postoperative cerebral edema are discussed. Evidence for lower overall postoperative morbidity, and for a lower incidence of cognitive dysfunction specifically, after nonpump coronary revascularization is presented.",

author = "Murkin, {John M.} and Boyd, {Walter D} and Su Ganapathy and Adams, {Sandra J.} and Peterson, {Rhonda C.} and Joanne Morgan and Peter Lok",

year = "2002",

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T1 - Neuroprotection during CPB

T2 - From mechanisms to interventions

AU - Murkin, John M.

AU - Boyd, Walter D

AU - Ganapathy, Su

AU - Adams, Sandra J.

AU - Peterson, Rhonda C.

AU - Morgan, Joanne

AU - Lok, Peter

PY - 2002

Y1 - 2002

N2 - The incidence and etiology of brain dysfunction after conventional coronary artery bypass surgery using cardiopulmonary bypass are reviewed. Stroke rates and incidences of cognitive dysfunction from various studies are considered. Mechanisms of injury including cerebral embolization as detected by transcranial Doppler and evidence for postoperative cerebral edema are discussed. Evidence for lower overall postoperative morbidity, and for a lower incidence of cognitive dysfunction specifically, after nonpump coronary revascularization is presented.

AB - The incidence and etiology of brain dysfunction after conventional coronary artery bypass surgery using cardiopulmonary bypass are reviewed. Stroke rates and incidences of cognitive dysfunction from various studies are considered. Mechanisms of injury including cerebral embolization as detected by transcranial Doppler and evidence for postoperative cerebral edema are discussed. Evidence for lower overall postoperative morbidity, and for a lower incidence of cognitive dysfunction specifically, after nonpump coronary revascularization is presented.

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Neuroprotection during CPB: From mechanisms to interventions

Abstract

ASJC Scopus subject areas

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