Neurophysiological recording in rat spinal cord trauma

J. C. De La Torre, James E Boggan

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A model for studying spinal cord trauma is described using the rat. The neurophysiological parameters that can be monitored in this model include blood pressure, spinal cord blood flow, somatosensory-evoked potentials, electroencephalogram, blood gases, and vital signs. In addition, histological preparations for histochemical fluorescence and neuronal tissue stains can be made from cryostat sections of the cord tissue. Biochemical determinations of the cord tissue are discussed. The rat model is useful because this species is inexpensive and well suited to study the pathophysiology of spinal cord injury. It is a valuable teaching tool in learning basic anesthesiology, physiology, and surgery. The model may also be used to test potentially useful treatments following experimental injury before a larger animal model series is attempted.

Original languageEnglish (US)
Pages (from-to)356-370
Number of pages15
JournalExperimental Neurology
Volume70
Issue number2
StatePublished - 1980
Externally publishedYes

Fingerprint

Spinal Cord Injuries
Somatosensory Evoked Potentials
Anesthesiology
Vital Signs
Fetal Blood
Electroencephalography
Spinal Cord
Teaching
Coloring Agents
Animal Models
Fluorescence
Gases
Learning
Blood Pressure
Wounds and Injuries

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neurology

Cite this

Neurophysiological recording in rat spinal cord trauma. / De La Torre, J. C.; Boggan, James E.

In: Experimental Neurology, Vol. 70, No. 2, 1980, p. 356-370.

Research output: Contribution to journalArticle

De La Torre, J. C. ; Boggan, James E. / Neurophysiological recording in rat spinal cord trauma. In: Experimental Neurology. 1980 ; Vol. 70, No. 2. pp. 356-370.
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