Abstract
Two young zebra siblings from consecutive pregnancies suffered from neurological disease, characterized by ventral deviation of the neck and tetraparesis which progressed to tetraplegia within a few weeks. On histological examination widespread neuronal degeneration was observed in the ventral horns of the spinal cord and in the lower brain stem. Ultrastructurally the neuronal degeneration was characterized by accumulation of neurofibrillary material resembling neurofilaments. The findings are compared to other diseases with neurofibrillary accumulation in man and animals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-5 |
| Number of pages | 5 |
| Journal | Acta Neuropathologica |
| Volume | 37 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1977 |
| Externally published | Yes |
Keywords
- Neurofibrillary degeneration
- Spinal neuronal degeneration
- Zebra siblings
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Clinical Neurology
- Cellular and Molecular Neuroscience
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Cite this
Higgins, R., Vandevelde, M., Hoff, E. J., Jagar, J. E., Cork, L. C., & Silberman, M. S. (1977). Neurofibrillary accumulation in the zebra (Equus burchelli). Acta Neuropathologica, 37(1), 1-5. https://doi.org/10.1007/BF00684532