Neuroendocrine tumour at the carina of a dog

E. N. Gould, Lynelle R Johnson, R. P. Traslavina, Frederick C Mohr

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


A 10-year-old, neutered female, crossbred pit bull terrier was presented for cough, haemoptysis and rapidly progressive respiratory difficulty. Thoracic radiographs suggested a soft tissue density at the carina and bronchoscopy revealed a large, broad-based mass obstructing the entire left mainstem bronchus and half of the entrance to the right mainstem bronchus. Microscopically, the mass consisted of neoplastic cells that were packeted into small nests and had strong granular cytoplasmic immunoreactivity to synaptophysin and chromogranin A. Cytoplasmic neurosecretory granules stained strongly by the Grimelius method. A diagnosis of obstructive neuroendocrine tumour was made.

Original languageEnglish (US)
Pages (from-to)233-236
Number of pages4
JournalJournal of Comparative Pathology
Issue number2-3
StatePublished - Aug 2013


  • Carina
  • Dog
  • Immunohistochemistry
  • Neuroendocrine tumour

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • veterinary(all)


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