Abstract
Gradual accumulation of evidence favoring one or another choice is considered a core component of many different types of decisions, and has been the subject of many neurophysiological studies in non-human primates. But its neural circuit mechanisms remain mysterious. Investigating it in rodents has recently become possible, facilitating perturbation experiments to delineate the relevant causal circuit, as well as the application of other tools more readily available in rodents. In addition, advances in stimulus design and analysis have aided studying the relevant neural encoding. In complement to ongoing non-human primate studies, these newly available model systems and tools place the field at an exciting time that suggests that the dynamical circuit mechanisms underlying accumulation of evidence could soon be revealed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 149-157 |
| Number of pages | 9 |
| Journal | Current Opinion in Neurobiology |
| Volume | 37 |
| DOIs | |
| State | Published - Apr 1 2016 |
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ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Neural underpinnings of the evidence accumulator. / Brody, Carlos D.; Hanks, Timothy.
In: Current Opinion in Neurobiology, Vol. 37, 01.04.2016, p. 149-157.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Neural underpinnings of the evidence accumulator
AU - Brody, Carlos D.
AU - Hanks, Timothy
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Gradual accumulation of evidence favoring one or another choice is considered a core component of many different types of decisions, and has been the subject of many neurophysiological studies in non-human primates. But its neural circuit mechanisms remain mysterious. Investigating it in rodents has recently become possible, facilitating perturbation experiments to delineate the relevant causal circuit, as well as the application of other tools more readily available in rodents. In addition, advances in stimulus design and analysis have aided studying the relevant neural encoding. In complement to ongoing non-human primate studies, these newly available model systems and tools place the field at an exciting time that suggests that the dynamical circuit mechanisms underlying accumulation of evidence could soon be revealed.
AB - Gradual accumulation of evidence favoring one or another choice is considered a core component of many different types of decisions, and has been the subject of many neurophysiological studies in non-human primates. But its neural circuit mechanisms remain mysterious. Investigating it in rodents has recently become possible, facilitating perturbation experiments to delineate the relevant causal circuit, as well as the application of other tools more readily available in rodents. In addition, advances in stimulus design and analysis have aided studying the relevant neural encoding. In complement to ongoing non-human primate studies, these newly available model systems and tools place the field at an exciting time that suggests that the dynamical circuit mechanisms underlying accumulation of evidence could soon be revealed.
UR - http://www.scopus.com/inward/record.url?scp=84957397795&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84957397795&partnerID=8YFLogxK
U2 - 10.1016/j.conb.2016.01.003
DO - 10.1016/j.conb.2016.01.003
M3 - Review article
C2 - 26878969
AN - SCOPUS:84957397795
VL - 37
SP - 149
EP - 157
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
SN - 0959-4388
ER -