Neural networks in radiologic diagnosis. II. Interpretation of neonatal chest radiographs

G. W. Gross, John M Boone, V. Greco-Hunt, B. Greenberg

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


A neural network (NN) system was trained to choose one or more diagnoses from a list of 12 possible diagnoses, based on 21 radiographic observations made on each of a series of neonatal chest radiographs. Initially, an experienced pediatric radiologist provided both the radiographic observations and ranked differential diagnoses for each of 77 neonatal chest radiographs in the preliminary phase used to train the NN. Subsequently, two pediatric radiologists (one of whom provided the initial training-phase data) independently read a series of 103 neonatal chest radiographs (different from the training set) and compiled a list of radiographic findings and differential diagnoses for each radiograph. The trained NN was then asked to provide a list of differential diagnoses for each case from the radiologists' lists of findings. Agreement between the network and each radiologist independently was greater than between the two radiologists. Both the positive and negative agreement between the network and either radiologist was greater than the inter-radiologist agreements for most the diagnostic endpoints.

Original languageEnglish (US)
Pages (from-to)1017-1023
Number of pages7
JournalInvestigative Radiology
Issue number9
StatePublished - 1990
Externally publishedYes


  • artificial intelligence
  • computer-aided diagnosis
  • neural network

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


Dive into the research topics of 'Neural networks in radiologic diagnosis. II. Interpretation of neonatal chest radiographs'. Together they form a unique fingerprint.

Cite this