Abstract
Neonatal hyperthyroidism is a rare condition caused either by transplacental passage of thyroid-stimulating immunoglobulins from a mother with Graves' disease or by activating mutations of the thyrotropin receptors and α-subunit of G-protein. The clinical features may vary. We report a case of neonatal thyrotoxicosis in an infant born to a mother with Graves' disease, who presented with cardiorespiratory failure and persistent pulmonary hypertension (PPHN). PPHN resolved with specific antithyroid treatment and extracorporeal membrane oxygenation was not required.
| Original language | English (US) |
|---|---|
| Journal | BMJ Case Reports |
| DOIs | |
| State | Published - Jan 1 2012 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Neonatal thyrotoxicosis presenting as persistent pulmonary hypertension. / Obeid, Rawad; Kalra, Vaneet K; Arora, Prem; Quist, Felix; Moltz, Kathleen C.; Chouthai, Nitin Shashikant.
In: BMJ Case Reports, 01.01.2012.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neonatal thyrotoxicosis presenting as persistent pulmonary hypertension
AU - Obeid, Rawad
AU - Kalra, Vaneet K
AU - Arora, Prem
AU - Quist, Felix
AU - Moltz, Kathleen C.
AU - Chouthai, Nitin Shashikant
PY - 2012/1/1
Y1 - 2012/1/1
N2 - Neonatal hyperthyroidism is a rare condition caused either by transplacental passage of thyroid-stimulating immunoglobulins from a mother with Graves' disease or by activating mutations of the thyrotropin receptors and α-subunit of G-protein. The clinical features may vary. We report a case of neonatal thyrotoxicosis in an infant born to a mother with Graves' disease, who presented with cardiorespiratory failure and persistent pulmonary hypertension (PPHN). PPHN resolved with specific antithyroid treatment and extracorporeal membrane oxygenation was not required.
AB - Neonatal hyperthyroidism is a rare condition caused either by transplacental passage of thyroid-stimulating immunoglobulins from a mother with Graves' disease or by activating mutations of the thyrotropin receptors and α-subunit of G-protein. The clinical features may vary. We report a case of neonatal thyrotoxicosis in an infant born to a mother with Graves' disease, who presented with cardiorespiratory failure and persistent pulmonary hypertension (PPHN). PPHN resolved with specific antithyroid treatment and extracorporeal membrane oxygenation was not required.
UR - http://www.scopus.com/inward/record.url?scp=84864764858&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84864764858&partnerID=8YFLogxK
U2 - 10.1136/bcr.02.2012.5939
DO - 10.1136/bcr.02.2012.5939
M3 - Article
C2 - 22669869
AN - SCOPUS:84864764858
JO - BMJ Case Reports
JF - BMJ Case Reports
SN - 1757-790X
ER -