Neonatal thyrotoxicosis presenting as persistent pulmonary hypertension

Rawad Obeid, Vaneet K Kalra, Prem Arora, Felix Quist, Kathleen C. Moltz, Nitin Shashikant Chouthai

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Neonatal hyperthyroidism is a rare condition caused either by transplacental passage of thyroid-stimulating immunoglobulins from a mother with Graves' disease or by activating mutations of the thyrotropin receptors and α-subunit of G-protein. The clinical features may vary. We report a case of neonatal thyrotoxicosis in an infant born to a mother with Graves' disease, who presented with cardiorespiratory failure and persistent pulmonary hypertension (PPHN). PPHN resolved with specific antithyroid treatment and extracorporeal membrane oxygenation was not required.

Original languageEnglish (US)
JournalBMJ Case Reports
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

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Thyrotoxicosis
Graves Disease
Pulmonary Hypertension
Thyroid-Stimulating Immunoglobulins
Mothers
Thyrotropin Receptors
Extracorporeal Membrane Oxygenation
Hyperthyroidism
GTP-Binding Proteins
Mutation
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Neonatal thyrotoxicosis presenting as persistent pulmonary hypertension. / Obeid, Rawad; Kalra, Vaneet K; Arora, Prem; Quist, Felix; Moltz, Kathleen C.; Chouthai, Nitin Shashikant.

In: BMJ Case Reports, 01.01.2012.

Research output: Contribution to journalArticle

Obeid, Rawad ; Kalra, Vaneet K ; Arora, Prem ; Quist, Felix ; Moltz, Kathleen C. ; Chouthai, Nitin Shashikant. / Neonatal thyrotoxicosis presenting as persistent pulmonary hypertension. In: BMJ Case Reports. 2012.
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