Neighborhood Predictors of Cognitive Training Outcomes and Trajectories in ACTIVE

Oanh Meyer, Shannon M. Sisco, Danielle J Harvey, Laura B. Zahodne, M. Maria Glymour, Jennifer J. Manly, Michael Marsiske

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


We examined the influence of neighborhood socioeconomic position (SEP), racial/ethnic composition, and living in a major city on cognitive trajectories and intervention outcomes. Data came from the Advanced Cognitive Training for Independent and Vital Elderly study (N = 2,438). Mixed effects analyses examined the associations between neighborhood variables and memory, reasoning, speed of processing, and everyday cognition, estimating differences in initial gains (potentially related to practice) and long-term rate of change over 10 years. The effect of reasoning training on initial gain was weaker for individuals in a major city. For everyday cognition, there was a stronger initial gain for memory-trained and control participants in areas with more racial/ethnic minorities and for speed-trained and control individuals in higher SEP areas. The racial/ethnic minority effect was no longer significant after adjustment for multiple comparisons. Neighborhood factors may be more important in practice-related improvement than in long-term change.

Original languageEnglish (US)
Pages (from-to)443-467
Number of pages25
JournalResearch on Aging
Issue number3
StatePublished - Mar 1 2017


  • cognition
  • cognitive training
  • neighborhood
  • plasticity
  • social determinants

ASJC Scopus subject areas

  • Health(social science)
  • Social Psychology
  • Geriatrics and Gerontology


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