Necrotizing pneumonia and pleuritis associated with extraintestinal pathogenic Escherichia coli in a tiger (panthera tigris) cub

Francisco R Carvallo chaigneau, Chitrita Debroy, Esteban Baeza, Lynn Hinckley, Kelly Gilbert, Soo Jeon Choi, Guillermo Risatti, Joan A. Smyth

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Extraintestinal pathogenic Escherichia coli (ExPEC) cause diseases in humans and animals, affecting organs outside the alimentary canal. In recent years, ExPEC have been reported as a cause of fatal pneumonia in dogs, cats, and in a horse. In the current report, a fatal case of pneumonia and pleuritis is described in a 4-week-old tiger (Panthera tigris) cub associated with ExPEC. The cub was presented with a sudden-onset respiratory illness and died after a few hours. Postmortem examination of the cub revealed an acute necrotizing pneumonia. The alveolar spaces were filled with large numbers of inflammatory cells (predominantly macrophages), edema, fibrin strands, and short bacillary bacteria. Escherichia coli O6:H31 was isolated in pure culture from the affected lung. It carried virulence genes cnf-1, sfa, fim, hlyD, and papG allele III, which are known to be associated with ExPEC strains. No evidence of infection by any other agent was detected. This is the first report, to the authors' knowledge, in which ExPEC has been associated with pneumonia in tigers.

Original languageEnglish (US)
Pages (from-to)136-140
Number of pages5
JournalJournal of Veterinary Diagnostic Investigation
Volume22
Issue number1
StatePublished - Jan 1 2010
Externally publishedYes

Keywords

  • Extraintestinal pathogenic escherichia coli
  • Pleuropneumonia
  • Tigers

ASJC Scopus subject areas

  • veterinary(all)

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