Necrotic Enteritis in Chickens Associated with Clostridium sordellii

Guillermo Rimoldi, Francisco A Uzal, Richard P Chin, Enzo A. Palombo, Milena Awad, Dena Lyras, H L Shivaprasad

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Three outbreaks of necrotic enteritis-like disease associated with Clostridium sordellii were diagnosed in commercial broiler chicken flocks with 18,000 to 31,000 birds between 18 and 26 days old. Clinical signs in the affected flocks included high mortality up to 2% a day, depression, and diarrhea. The main gross changes included segmental dilation of the small intestine with watery contents, gas, mucoid exudate, and roughened and uneven mucosa, occasionally covered with a pseudomembrane. Microscopic lesions in the small intestine were characterized by extensive areas of coagulative necrosis of the villi, fibrinous exudate in the lumen, and high numbers of large, Gram-positive rods, occasionally containing subterminal spores, seen in the necrotic tissue and lumen. These rods were identified as C. sordellii by immunohistochemistry. Clostridium sordellii was isolated in an almost pure culture from the intestine of affected birds. A retrospective study of commercial broiler chicken and Turkey submissions to the California Animal Health and Food Safety Laboratory System revealed that C. sordellii had been isolated from intestinal lesions in outbreaks of necrotic enteritis-like disease in 8 of 39 cases, 5 times together with Clostridium perfringens and 3 times alone. The latter three cases are reported here.

Original languageEnglish (US)
Pages (from-to)447-451
Number of pages5
JournalAvian Diseases
Volume59
Issue number3
DOIs
StatePublished - Sep 1 2015

Fingerprint

Clostridium sordellii
necrotic enteritis
Enteritis
Chickens
chickens
Exudates and Transudates
lesions (animal)
Small Intestine
Birds
Disease Outbreaks
small intestine
flocks
broiler chickens
Gram-Positive Rods
Hazard Analysis and Critical Control Points
Clostridium perfringens
birds
villi
Turkey
Spores

Keywords

  • chicken
  • Clostridium perfringens
  • Clostridium sordellii
  • necrotic enteritis
  • poultry

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Food Animals
  • Immunology and Microbiology(all)

Cite this

Necrotic Enteritis in Chickens Associated with Clostridium sordellii. / Rimoldi, Guillermo; Uzal, Francisco A; Chin, Richard P; Palombo, Enzo A.; Awad, Milena; Lyras, Dena; Shivaprasad, H L.

In: Avian Diseases, Vol. 59, No. 3, 01.09.2015, p. 447-451.

Research output: Contribution to journalArticle

Rimoldi, Guillermo ; Uzal, Francisco A ; Chin, Richard P ; Palombo, Enzo A. ; Awad, Milena ; Lyras, Dena ; Shivaprasad, H L. / Necrotic Enteritis in Chickens Associated with Clostridium sordellii. In: Avian Diseases. 2015 ; Vol. 59, No. 3. pp. 447-451.
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