Abstract
The award of the Nobel Prize to Professors John O'Keefe, May-Britt Moser, and Edvard Moser brings global recognition to one of the most significant success stories in modern neuroscience. Here, we consider how their findings, along with related studies of spatial cognition in rodents, have informed our understanding of the human hippocampus. Rather than identifying a "GPS" in the brain, we emphasize that these researchers helped to establish a fundamental role for cortico-hippocampal networks in the guidance of behavior based on a representation of the current place, time, and situation. We conclude by highlighting the major questions that remain to be addressed in future research.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 697-703 |
| Number of pages | 7 |
| Journal | Hippocampus |
| Volume | 25 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 2015 |
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Keywords
- Binding
- Context
- Parahippocampal
- Perirhinal
- Time
ASJC Scopus subject areas
- Cognitive Neuroscience
Cite this
Navigating the human hippocampus without a GPS. / Zucker, Halle R.; Ranganath, Charan.
In: Hippocampus, Vol. 25, No. 6, 01.06.2015, p. 697-703.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Navigating the human hippocampus without a GPS
AU - Zucker, Halle R.
AU - Ranganath, Charan
PY - 2015/6/1
Y1 - 2015/6/1
N2 - The award of the Nobel Prize to Professors John O'Keefe, May-Britt Moser, and Edvard Moser brings global recognition to one of the most significant success stories in modern neuroscience. Here, we consider how their findings, along with related studies of spatial cognition in rodents, have informed our understanding of the human hippocampus. Rather than identifying a "GPS" in the brain, we emphasize that these researchers helped to establish a fundamental role for cortico-hippocampal networks in the guidance of behavior based on a representation of the current place, time, and situation. We conclude by highlighting the major questions that remain to be addressed in future research.
AB - The award of the Nobel Prize to Professors John O'Keefe, May-Britt Moser, and Edvard Moser brings global recognition to one of the most significant success stories in modern neuroscience. Here, we consider how their findings, along with related studies of spatial cognition in rodents, have informed our understanding of the human hippocampus. Rather than identifying a "GPS" in the brain, we emphasize that these researchers helped to establish a fundamental role for cortico-hippocampal networks in the guidance of behavior based on a representation of the current place, time, and situation. We conclude by highlighting the major questions that remain to be addressed in future research.
KW - Binding
KW - Context
KW - Parahippocampal
KW - Perirhinal
KW - Time
UR - http://www.scopus.com/inward/record.url?scp=84929839999&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929839999&partnerID=8YFLogxK
U2 - 10.1002/hipo.22447
DO - 10.1002/hipo.22447
M3 - Article
VL - 25
SP - 697
EP - 703
JO - Hippocampus
JF - Hippocampus
SN - 1050-9631
IS - 6
ER -