Navigating the human hippocampus without a GPS

Halle R. Zucker, Charan Ranganath

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The award of the Nobel Prize to Professors John O'Keefe, May-Britt Moser, and Edvard Moser brings global recognition to one of the most significant success stories in modern neuroscience. Here, we consider how their findings, along with related studies of spatial cognition in rodents, have informed our understanding of the human hippocampus. Rather than identifying a "GPS" in the brain, we emphasize that these researchers helped to establish a fundamental role for cortico-hippocampal networks in the guidance of behavior based on a representation of the current place, time, and situation. We conclude by highlighting the major questions that remain to be addressed in future research.

Original languageEnglish (US)
Pages (from-to)697-703
Number of pages7
JournalHippocampus
Volume25
Issue number6
DOIs
StatePublished - Jun 1 2015

Fingerprint

Nobel Prize
Neurosciences
Cognition
Rodentia
Hippocampus
Research Personnel
Brain
Recognition (Psychology)

Keywords

  • Binding
  • Context
  • Parahippocampal
  • Perirhinal
  • Time

ASJC Scopus subject areas

  • Cognitive Neuroscience

Cite this

Navigating the human hippocampus without a GPS. / Zucker, Halle R.; Ranganath, Charan.

In: Hippocampus, Vol. 25, No. 6, 01.06.2015, p. 697-703.

Research output: Contribution to journalArticle

Zucker, HR & Ranganath, C 2015, 'Navigating the human hippocampus without a GPS', Hippocampus, vol. 25, no. 6, pp. 697-703. https://doi.org/10.1002/hipo.22447
Zucker, Halle R. ; Ranganath, Charan. / Navigating the human hippocampus without a GPS. In: Hippocampus. 2015 ; Vol. 25, No. 6. pp. 697-703.
@article{520ed4b66ee44854a88e5800f1222701,
title = "Navigating the human hippocampus without a GPS",
abstract = "The award of the Nobel Prize to Professors John O'Keefe, May-Britt Moser, and Edvard Moser brings global recognition to one of the most significant success stories in modern neuroscience. Here, we consider how their findings, along with related studies of spatial cognition in rodents, have informed our understanding of the human hippocampus. Rather than identifying a {"}GPS{"} in the brain, we emphasize that these researchers helped to establish a fundamental role for cortico-hippocampal networks in the guidance of behavior based on a representation of the current place, time, and situation. We conclude by highlighting the major questions that remain to be addressed in future research.",
keywords = "Binding, Context, Parahippocampal, Perirhinal, Time",
author = "Zucker, {Halle R.} and Charan Ranganath",
year = "2015",
month = "6",
day = "1",
doi = "10.1002/hipo.22447",
language = "English (US)",
volume = "25",
pages = "697--703",
journal = "Hippocampus",
issn = "1050-9631",
publisher = "Wiley-Liss Inc.",
number = "6",

}

TY - JOUR

T1 - Navigating the human hippocampus without a GPS

AU - Zucker, Halle R.

AU - Ranganath, Charan

PY - 2015/6/1

Y1 - 2015/6/1

N2 - The award of the Nobel Prize to Professors John O'Keefe, May-Britt Moser, and Edvard Moser brings global recognition to one of the most significant success stories in modern neuroscience. Here, we consider how their findings, along with related studies of spatial cognition in rodents, have informed our understanding of the human hippocampus. Rather than identifying a "GPS" in the brain, we emphasize that these researchers helped to establish a fundamental role for cortico-hippocampal networks in the guidance of behavior based on a representation of the current place, time, and situation. We conclude by highlighting the major questions that remain to be addressed in future research.

AB - The award of the Nobel Prize to Professors John O'Keefe, May-Britt Moser, and Edvard Moser brings global recognition to one of the most significant success stories in modern neuroscience. Here, we consider how their findings, along with related studies of spatial cognition in rodents, have informed our understanding of the human hippocampus. Rather than identifying a "GPS" in the brain, we emphasize that these researchers helped to establish a fundamental role for cortico-hippocampal networks in the guidance of behavior based on a representation of the current place, time, and situation. We conclude by highlighting the major questions that remain to be addressed in future research.

KW - Binding

KW - Context

KW - Parahippocampal

KW - Perirhinal

KW - Time

UR - http://www.scopus.com/inward/record.url?scp=84929839999&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929839999&partnerID=8YFLogxK

U2 - 10.1002/hipo.22447

DO - 10.1002/hipo.22447

M3 - Article

VL - 25

SP - 697

EP - 703

JO - Hippocampus

JF - Hippocampus

SN - 1050-9631

IS - 6

ER -