Natriuretic Peptides in Heart Failure: Atrial and B-type Natriuretic Peptides

Alan S. Maisel, Jason M. Duran, Nicholas Wettersten

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

The natriuretic peptides play a vital role in normal physiology and as counter-regulatory hormones in heart failure (HF). Clinical assessment of their levels (for B-type natriuretic peptide [BNP], N-terminal proBNP, and the midregion of N-terminal pro–atrial natriuretic peptide) have become valuable tools in diagnosing patients with HF as well as risk stratifying and guiding therapy. Their roles have further expanded beyond HF to other cardiovascular conditions and for risk stratification in asymptomatic individuals. Understanding the clinical use of these hormones is vital to achieving their full potential.

Original languageEnglish (US)
Pages (from-to)13-25
Number of pages13
JournalHeart Failure Clinics
Volume14
Issue number1
DOIs
StatePublished - Jan 1 2018
Externally publishedYes

Keywords

  • B-type natriuretic peptide
  • Diagnosis
  • Heart failure
  • Midregional pro–atrial natriuretic peptide
  • N-terminal B-type natriuretic peptide
  • Prognosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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