Abstract
The term nanotechnology refers to the design, creation, and manipulation of structures on the nanometer scale. Much of the ongoing research and development of nanotechnology is focused on the development of novel methods of imaging and delivery of therapeutics through minimally invasive means. Multifunctional nanoparticles offer great promise for molecular imaging and directing novel therapeutics to molecular targets, which was never before possible. Nanoparticle-based contrast agents have been developed for all imaging modalities. A rapidly increasing number of companies and government funding initiatives have led to a large number of novel agents in various stages of development, ranging from in vitro and in vivo animal studies to clinical use. However, barriers to the delivery of nanoparticles for tumor imaging and therapy exist. Interventional radiologists may circumvent these barriers by using imaging to guide delivery of nanoparticles.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1449-1462 |
| Number of pages | 14 |
| Journal | Radiographics |
| Volume | 31 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 2011 |
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ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Nanotechnology development and utilization : A primer for diagnostic and interventional radiologists. / Monsky, Wayne L.; Vien, Derek S.; Link, Daniel P.
In: Radiographics, Vol. 31, No. 5, 09.2011, p. 1449-1462.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nanotechnology development and utilization
T2 - A primer for diagnostic and interventional radiologists
AU - Monsky, Wayne L.
AU - Vien, Derek S.
AU - Link, Daniel P
PY - 2011/9
Y1 - 2011/9
N2 - The term nanotechnology refers to the design, creation, and manipulation of structures on the nanometer scale. Much of the ongoing research and development of nanotechnology is focused on the development of novel methods of imaging and delivery of therapeutics through minimally invasive means. Multifunctional nanoparticles offer great promise for molecular imaging and directing novel therapeutics to molecular targets, which was never before possible. Nanoparticle-based contrast agents have been developed for all imaging modalities. A rapidly increasing number of companies and government funding initiatives have led to a large number of novel agents in various stages of development, ranging from in vitro and in vivo animal studies to clinical use. However, barriers to the delivery of nanoparticles for tumor imaging and therapy exist. Interventional radiologists may circumvent these barriers by using imaging to guide delivery of nanoparticles.
AB - The term nanotechnology refers to the design, creation, and manipulation of structures on the nanometer scale. Much of the ongoing research and development of nanotechnology is focused on the development of novel methods of imaging and delivery of therapeutics through minimally invasive means. Multifunctional nanoparticles offer great promise for molecular imaging and directing novel therapeutics to molecular targets, which was never before possible. Nanoparticle-based contrast agents have been developed for all imaging modalities. A rapidly increasing number of companies and government funding initiatives have led to a large number of novel agents in various stages of development, ranging from in vitro and in vivo animal studies to clinical use. However, barriers to the delivery of nanoparticles for tumor imaging and therapy exist. Interventional radiologists may circumvent these barriers by using imaging to guide delivery of nanoparticles.
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U2 - 10.1148/rg.315105238
DO - 10.1148/rg.315105238
M3 - Article
VL - 31
SP - 1449
EP - 1462
JO - Radiographics
JF - Radiographics
SN - 0271-5333
IS - 5
ER -