Nanotechnology development and utilization: A primer for diagnostic and interventional radiologists

Wayne L. Monsky, Derek S. Vien, Daniel P Link

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The term nanotechnology refers to the design, creation, and manipulation of structures on the nanometer scale. Much of the ongoing research and development of nanotechnology is focused on the development of novel methods of imaging and delivery of therapeutics through minimally invasive means. Multifunctional nanoparticles offer great promise for molecular imaging and directing novel therapeutics to molecular targets, which was never before possible. Nanoparticle-based contrast agents have been developed for all imaging modalities. A rapidly increasing number of companies and government funding initiatives have led to a large number of novel agents in various stages of development, ranging from in vitro and in vivo animal studies to clinical use. However, barriers to the delivery of nanoparticles for tumor imaging and therapy exist. Interventional radiologists may circumvent these barriers by using imaging to guide delivery of nanoparticles.

Original languageEnglish (US)
Pages (from-to)1449-1462
Number of pages14
JournalRadiographics
Volume31
Issue number5
DOIs
StatePublished - Sep 2011

Fingerprint

Nanotechnology
Nanoparticles
Molecular Imaging
Contrast Media
Therapeutics
Radiologists
Research
Neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Nanotechnology development and utilization : A primer for diagnostic and interventional radiologists. / Monsky, Wayne L.; Vien, Derek S.; Link, Daniel P.

In: Radiographics, Vol. 31, No. 5, 09.2011, p. 1449-1462.

Research output: Contribution to journalArticle

Monsky, Wayne L. ; Vien, Derek S. ; Link, Daniel P. / Nanotechnology development and utilization : A primer for diagnostic and interventional radiologists. In: Radiographics. 2011 ; Vol. 31, No. 5. pp. 1449-1462.
@article{644920e8767244b4a54489f96d44bdcb,
title = "Nanotechnology development and utilization: A primer for diagnostic and interventional radiologists",
abstract = "The term nanotechnology refers to the design, creation, and manipulation of structures on the nanometer scale. Much of the ongoing research and development of nanotechnology is focused on the development of novel methods of imaging and delivery of therapeutics through minimally invasive means. Multifunctional nanoparticles offer great promise for molecular imaging and directing novel therapeutics to molecular targets, which was never before possible. Nanoparticle-based contrast agents have been developed for all imaging modalities. A rapidly increasing number of companies and government funding initiatives have led to a large number of novel agents in various stages of development, ranging from in vitro and in vivo animal studies to clinical use. However, barriers to the delivery of nanoparticles for tumor imaging and therapy exist. Interventional radiologists may circumvent these barriers by using imaging to guide delivery of nanoparticles.",
author = "Monsky, {Wayne L.} and Vien, {Derek S.} and Link, {Daniel P}",
year = "2011",
month = "9",
doi = "10.1148/rg.315105238",
language = "English (US)",
volume = "31",
pages = "1449--1462",
journal = "Radiographics",
issn = "0271-5333",
publisher = "Radiological Society of North America Inc.",
number = "5",

}

TY - JOUR

T1 - Nanotechnology development and utilization

T2 - A primer for diagnostic and interventional radiologists

AU - Monsky, Wayne L.

AU - Vien, Derek S.

AU - Link, Daniel P

PY - 2011/9

Y1 - 2011/9

N2 - The term nanotechnology refers to the design, creation, and manipulation of structures on the nanometer scale. Much of the ongoing research and development of nanotechnology is focused on the development of novel methods of imaging and delivery of therapeutics through minimally invasive means. Multifunctional nanoparticles offer great promise for molecular imaging and directing novel therapeutics to molecular targets, which was never before possible. Nanoparticle-based contrast agents have been developed for all imaging modalities. A rapidly increasing number of companies and government funding initiatives have led to a large number of novel agents in various stages of development, ranging from in vitro and in vivo animal studies to clinical use. However, barriers to the delivery of nanoparticles for tumor imaging and therapy exist. Interventional radiologists may circumvent these barriers by using imaging to guide delivery of nanoparticles.

AB - The term nanotechnology refers to the design, creation, and manipulation of structures on the nanometer scale. Much of the ongoing research and development of nanotechnology is focused on the development of novel methods of imaging and delivery of therapeutics through minimally invasive means. Multifunctional nanoparticles offer great promise for molecular imaging and directing novel therapeutics to molecular targets, which was never before possible. Nanoparticle-based contrast agents have been developed for all imaging modalities. A rapidly increasing number of companies and government funding initiatives have led to a large number of novel agents in various stages of development, ranging from in vitro and in vivo animal studies to clinical use. However, barriers to the delivery of nanoparticles for tumor imaging and therapy exist. Interventional radiologists may circumvent these barriers by using imaging to guide delivery of nanoparticles.

UR - http://www.scopus.com/inward/record.url?scp=80052893546&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052893546&partnerID=8YFLogxK

U2 - 10.1148/rg.315105238

DO - 10.1148/rg.315105238

M3 - Article

C2 - 21918055

AN - SCOPUS:80052893546

VL - 31

SP - 1449

EP - 1462

JO - Radiographics

JF - Radiographics

SN - 0271-5333

IS - 5

ER -