Nanofiber-Based Total Internal Reflection Microscopy for Characterizing Colloidal Systems at the Microscale

Joshua T. Villanueva, Qian Huang, Nicholas O Fischer, Gaurav Arya, Donald J. Sirbuly

Research output: Contribution to journalArticle

Abstract

Bulk colloidal interactions are dictated by the physical properties of individual particles dispersed in solution. However, for many applications it remains challenging to predict system-level colloidal behavior. Comprehensive characterization typically requires disparate techniques that can observe correlations between microscale particle-surface interactions and physical properties of the particles. In this work, we present a unique tin dioxide (SnO2) nanofiber-based total internal reflection microscopy (TIRM) method to efficiently characterize colloidal behavior as a function of particle-level properties in complex fluidic conditions. We develop and model the device physics to understand the physical underpinnings of the raw device data and then use these models to design proof-of-concept experiments to verify device function. Statistical trends in the data collected from a nominal system of 80 nm gold nanoparticles correspond to theoretical predictions as we vary key design parameters such as particle size, surface charge, and solution ionic strength. Lastly, we consider the practical limitations of the technique gleaned from our studies and offer suggestions for utilizing the platform to quantitatively analyze nonideal colloidal systems with distributed or heterogeneous system parameters.

Original languageEnglish (US)
Pages (from-to)22114-22124
Number of pages11
JournalJournal of Physical Chemistry C
Volume122
Issue number38
DOIs
StatePublished - Sep 27 2018
Externally publishedYes

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Nanofibers
microbalances
Microscopic examination
Physical properties
Tin dioxide
microscopy
Fluidics
Surface charge
Ionic strength
Gold
Physics
Particle size
Nanoparticles
physical properties
fluidics
dioxides
Experiments
surface reactions
suggestion
tin

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Energy(all)
  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films

Cite this

Nanofiber-Based Total Internal Reflection Microscopy for Characterizing Colloidal Systems at the Microscale. / Villanueva, Joshua T.; Huang, Qian; Fischer, Nicholas O; Arya, Gaurav; Sirbuly, Donald J.

In: Journal of Physical Chemistry C, Vol. 122, No. 38, 27.09.2018, p. 22114-22124.

Research output: Contribution to journalArticle

Villanueva, Joshua T. ; Huang, Qian ; Fischer, Nicholas O ; Arya, Gaurav ; Sirbuly, Donald J. / Nanofiber-Based Total Internal Reflection Microscopy for Characterizing Colloidal Systems at the Microscale. In: Journal of Physical Chemistry C. 2018 ; Vol. 122, No. 38. pp. 22114-22124.
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