NADPH dependent epoxidation of methyl farnesoate to juvenile hormone in the cockroach Blaberus giganteus L.

Bruce D. Hammock

Research output: Contribution to journalArticle

47 Scopus citations

Abstract

Corpora allata and corpora allata homogenates from the cockroach Blaberus giganteus are able to convert tritium labeled trans, trans-methyl farnesoate into insect juvenile hormone III. The epoxidation appears to be enzymatic occurring largely in the 100,000 g precipitate or microsomal fraction of corpora allata homogenates. The epoxidation is NADPH dependent, requires molecular oxygen and is inhibited by carbon monoxide, methylene blue, SKF 525A, and piperonyl butoxide.

Original languageEnglish (US)
Pages (from-to)323-328
Number of pages6
JournalLife Sciences
Volume17
Issue number3
DOIs
StatePublished - Aug 1 1975

ASJC Scopus subject areas

  • Pharmacology

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