Mycotic aneurysm of the thoracic aorta due to Aspergillus terreus: Case report and review

Monica E. Silva, Marcio Malogolowkin, Theodore R. Hall, Ali M. Sadeghi, Paul Krogstad

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Abstract

Mycotic aneurysms of the aorta caused by fungi are uncommon. We describe an unusual case of aortic aneurysm infection caused by Aspergillus terreus, which most likely spread from an adjacent pulmonary focus. Successful treatment included partial pneumonectomy, resection of the aneurysm with graft repair, and prolonged sequential administration of amphotericin B and itraconazole. A review of the published experience with aortic aneurysms caused by Aspergillus species is also presented. When invasive aspergillosis is suspected in proximity to areas with major vascular structures in immunocompromised patients, further investigation to rule out vascular invasion may be warranted. If the diagnosis is confirmed, aggressive and prompt treatment with antifungal agents combined with surgical debridement is essential to improve outcome.

Original languageEnglish (US)
Pages (from-to)1144-1148
Number of pages5
JournalClinical Infectious Diseases
Volume31
Issue number5
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

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ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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