Muscle function in hibernating hamsters: A natural analog to bed rest?

Steven J. Wickler, Barbara A Horwitz, Kayleen S.Kott

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

1. 1. In Experiment I(fall/winter), hamsters exposed to cold and short photoperiod entered hibernation; hamsters exposed to cold and long photoperiod did not. 2. 2. Hibernators had reduced body masses, significantly atrophied skeletal muscles, but increased mass-specific maximum activities of citrate synthase (an indicator of aerobic capacity) and HOAD (an indicator of β-oxidation). 3. 3. In Experiment II (winter/spring), hamsters were similarly exposed to cold and either long or short photoperiods, but none hibernated. 4. 4. No differences occurred in skeletal muscle masses or enzymatic activities of these two nonhibernating groups in Experiment II. 5. 5. Thus, photoperiod per se does not appear to elicit the skeletal muscle changes seen in the hibernating hamsters; nor are these changes comparable to those seen during bed or limb immobilization.

Original languageEnglish (US)
Pages (from-to)163-166
Number of pages4
JournalJournal of Thermal Biology
Volume12
Issue number2
DOIs
StatePublished - 1987

Keywords

  • exercise
  • hamster
  • hibernation
  • Mesocricetus auratus
  • Muscle
  • oxidative capacity
  • photoperiod
  • thermogenesis

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Physiology

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