Muscle biopsy evaluation in neuromuscular disorders

Nanette Joyce, Bjorn E Oskarsson, Lee-Way Jin

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

This article reviews the indications for a muscle biopsy, and then gives a step-by-step description of the processes of muscle selection through to interpreting the biopsy report. The article aims to aid the clinician in preparing for a muscle biopsy procedure to avoid common pitfalls and obtain optimal results from this minimally invasive procedure. The basic anatomic structure of normal muscle is reviewed to provide a foundation for understanding common patterns of pathologic change observed in muscle disease and common and disease-specific histopathologic findings are presented, focusing on a select group of neuromuscular diseases.

Original languageEnglish (US)
Pages (from-to)609-631
Number of pages23
JournalPhysical Medicine and Rehabilitation Clinics of North America
Volume23
Issue number3
DOIs
StatePublished - Aug 2012

Fingerprint

Biopsy
Muscles
Neuromuscular Diseases

Keywords

  • Histopathology
  • Muscle biopsy
  • Myopathic
  • Neurogenic atrophy
  • Neuromuscular disease

ASJC Scopus subject areas

  • Rehabilitation
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Muscle biopsy evaluation in neuromuscular disorders. / Joyce, Nanette; Oskarsson, Bjorn E; Jin, Lee-Way.

In: Physical Medicine and Rehabilitation Clinics of North America, Vol. 23, No. 3, 08.2012, p. 609-631.

Research output: Contribution to journalArticle

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