Multimodal near infrared spectral imaging as an exploratory tool for dysplastic esophageal lesion identification

Chad A. Lieber; Shiro Urayama; Nazir Rahim; Raymond Tu; Ramez Saroufeem; Boris Reubner; Stavros G. Demos

doi:10.1364/OE.14.002211

Multimodal near infrared spectral imaging as an exploratory tool for dysplastic esophageal lesion identification

Chad A. Lieber, Shiro Urayama, Nazir Rahim, Raymond Tu, Ramez Saroufeem, Boris Reubner, Stavros G. Demos

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

We explore nine different combinations of fluorescence, light scattering, and polarization spectral imaging approaches in the near-infrared spectral region toward the diagnosis of pathologic and normal esophageal lesions. The combinations of all the imaging techniques were evaluated for maximal sensitivity and specificity. The results suggest that this multimodal approach is capable of highly accurate detection of the presence of pathologic tissue.

Original language	English (US)
Pages (from-to)	2211-2219
Number of pages	9
Journal	Optics Express
Volume	14
Issue number	6
DOIs	https://doi.org/10.1364/OE.14.002211
State	Published - 2006

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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10.1364/OE.14.002211

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title = "Multimodal near infrared spectral imaging as an exploratory tool for dysplastic esophageal lesion identification",

abstract = "We explore nine different combinations of fluorescence, light scattering, and polarization spectral imaging approaches in the near-infrared spectral region toward the diagnosis of pathologic and normal esophageal lesions. The combinations of all the imaging techniques were evaluated for maximal sensitivity and specificity. The results suggest that this multimodal approach is capable of highly accurate detection of the presence of pathologic tissue.",

author = "Lieber, {Chad A.} and Shiro Urayama and Nazir Rahim and Raymond Tu and Ramez Saroufeem and Boris Reubner and Demos, {Stavros G.}",

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AU - Lieber, Chad A.

AU - Urayama, Shiro

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AU - Tu, Raymond

AU - Saroufeem, Ramez

AU - Reubner, Boris

AU - Demos, Stavros G.

PY - 2006

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AB - We explore nine different combinations of fluorescence, light scattering, and polarization spectral imaging approaches in the near-infrared spectral region toward the diagnosis of pathologic and normal esophageal lesions. The combinations of all the imaging techniques were evaluated for maximal sensitivity and specificity. The results suggest that this multimodal approach is capable of highly accurate detection of the presence of pathologic tissue.

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Multimodal near infrared spectral imaging as an exploratory tool for dysplastic esophageal lesion identification

Abstract

ASJC Scopus subject areas

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