Multimodal near infrared spectral imaging as an exploratory tool for dysplastic esophageal lesion identification

Chad A. Lieber, Shiro Urayama, Nazir Rahim, Raymond Tu, Ramez Saroufeem, Boris Reubner, Stavros G. Demos

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

We explore nine different combinations of fluorescence, light scattering, and polarization spectral imaging approaches in the near-infrared spectral region toward the diagnosis of pathologic and normal esophageal lesions. The combinations of all the imaging techniques were evaluated for maximal sensitivity and specificity. The results suggest that this multimodal approach is capable of highly accurate detection of the presence of pathologic tissue.

Original languageEnglish (US)
Pages (from-to)2211-2219
Number of pages9
JournalOptics Express
Volume14
Issue number6
DOIs
StatePublished - 2006

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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