Abstract
Agents get smart: A macrocycle-based gadolinium complex undergoes an isomerization in the presence of NADH, leading to an r1 relaxivity increase of 54 %, while the intense fluorescence disappears (see scheme). This agent could facilitate the use of magnetic resonance imaging (MRI) for probing tissue redox status.
Original language | English (US) |
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Pages (from-to) | 6547-6551 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 48 |
Issue number | 35 |
DOIs | |
State | Published - 2009 |
Keywords
- Biosensors
- Gadolinium
- Imaging
- Imaging agents
- Magnetic resonance
- NADH
ASJC Scopus subject areas
- Chemistry(all)
- Catalysis
- Medicine(all)