Multiinstitutional experience with the management of superior mesenteric, artery injuries

Juan A. Asensio, L. D. Britt, Anthony Borzotta, Andrew Peitzman, Frank B. Miller, Robert C. Mackersie, Michael D. Pasquale, H. Leon Pachter, David B. Hoyt, Jorge L. Rodriguez, Robert Falcone, Kimberly Davis, John T Anderson, Jameel Ali, Linda Chan

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

BACKGROUND: Superior mesenteric artery (SMA) injuries are rare and often lethal injuries incurring very high morbidity and mortality. The purposes of this study are to review a multiinstitutional experience with these injuries; to analyze Fullen's classification based on anatomic zone and ischemia grade for its predictive value; to correlate the American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) for abdominal vascular injury with mortality; and to identify independent risk factors predictive of mortality, describing current trends for the management of this injury in America. STUDY DESIGN: We performed a retrospective, multiinstitutional study of patients sustaining SMA injuries involving 34 trauma centers in the US over 10 years. Outcomes variables, both continuous and dichotomous, were analyzed initially with univariate methods. For the subsequent multivariate analysis, stepwise logistic regression was used to identify a set of risk factors significantly associated with mortality. RESULTS: There were 250 patients enrolled, with a mean Revised Trauma Score (RTS) of 6.44 and a mean Injury Severity Score (ISS) of 25. Surgical management consisted of ligation in 175 of 244 patients (72%), first degree repair in 53 of 244 patients (22%), autogenous grafts were used in 10 of 244 (4%), and prosthetic grafts of PTFE in 6 of 244 patients (2%). Overall mortality was 97 of 250 patients (39%). Mortality versus Fullen's zones: zone I, 39 of 51 (76.5%); zone II, 15 of 34 (44.1%); zone III, 11 of 40 (27.5%); and zone IV, 25 of 108 (23.1%). Mortality versus Fullen's ischemia grade: grade 1, 22 of 34 (64.7%). Mortality versus AAST-OIS for abdominal vascular injury: grade I, 9 of 55 (16.4%); grade II, 13 of 51 (25.5%); grade III, 8 of 20 (40%); grade IV, 37 of 69 (53.6%); and grade V, 17 of 19 (89.5%). Logistic regression analysis identified as independent risk factors for mortality the following: transfusion of greater than 10 units of packed RBCs, intraoperative acidosis, dysrhythmias, injury to Fullen's zone I or II, and multisystem organ failure. CONCLUSIONS: SMA injuries are highly lethal. Fullen's anatomic zones, ischemia grade, and AAST-OIS abdominal vascular injuries correlate well with mortality. Injuries to Fullen's zones I and II, Fullen's maximal ischemia grade, and AAST-OIS injury grades IV and V, high-intraoperative transfusion requirements, and presence of acidosis and disrhythmias are significant predictors of mortality. All of these predictive factors for mortality must be taken into account in the surgical management of these injuries.

Original languageEnglish (US)
Pages (from-to)354-366
Number of pages13
JournalJournal of the American College of Surgeons
Volume193
Issue number4
DOIs
StatePublished - 2001
Externally publishedYes

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Superior Mesenteric Artery
Wounds and Injuries
Mortality
Abdominal Injuries
Vascular System Injuries
Ischemia
Acidosis
Logistic Models
Transplants
Injury Severity Score
Trauma Centers
Intraoperative Complications
Polytetrafluoroethylene

ASJC Scopus subject areas

  • Surgery

Cite this

Asensio, J. A., Britt, L. D., Borzotta, A., Peitzman, A., Miller, F. B., Mackersie, R. C., ... Chan, L. (2001). Multiinstitutional experience with the management of superior mesenteric, artery injuries. Journal of the American College of Surgeons, 193(4), 354-366. https://doi.org/10.1016/S1072-7515(01)01044-4

Multiinstitutional experience with the management of superior mesenteric, artery injuries. / Asensio, Juan A.; Britt, L. D.; Borzotta, Anthony; Peitzman, Andrew; Miller, Frank B.; Mackersie, Robert C.; Pasquale, Michael D.; Pachter, H. Leon; Hoyt, David B.; Rodriguez, Jorge L.; Falcone, Robert; Davis, Kimberly; Anderson, John T; Ali, Jameel; Chan, Linda.

In: Journal of the American College of Surgeons, Vol. 193, No. 4, 2001, p. 354-366.

Research output: Contribution to journalArticle

Asensio, JA, Britt, LD, Borzotta, A, Peitzman, A, Miller, FB, Mackersie, RC, Pasquale, MD, Pachter, HL, Hoyt, DB, Rodriguez, JL, Falcone, R, Davis, K, Anderson, JT, Ali, J & Chan, L 2001, 'Multiinstitutional experience with the management of superior mesenteric, artery injuries', Journal of the American College of Surgeons, vol. 193, no. 4, pp. 354-366. https://doi.org/10.1016/S1072-7515(01)01044-4
Asensio, Juan A. ; Britt, L. D. ; Borzotta, Anthony ; Peitzman, Andrew ; Miller, Frank B. ; Mackersie, Robert C. ; Pasquale, Michael D. ; Pachter, H. Leon ; Hoyt, David B. ; Rodriguez, Jorge L. ; Falcone, Robert ; Davis, Kimberly ; Anderson, John T ; Ali, Jameel ; Chan, Linda. / Multiinstitutional experience with the management of superior mesenteric, artery injuries. In: Journal of the American College of Surgeons. 2001 ; Vol. 193, No. 4. pp. 354-366.
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abstract = "BACKGROUND: Superior mesenteric artery (SMA) injuries are rare and often lethal injuries incurring very high morbidity and mortality. The purposes of this study are to review a multiinstitutional experience with these injuries; to analyze Fullen's classification based on anatomic zone and ischemia grade for its predictive value; to correlate the American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) for abdominal vascular injury with mortality; and to identify independent risk factors predictive of mortality, describing current trends for the management of this injury in America. STUDY DESIGN: We performed a retrospective, multiinstitutional study of patients sustaining SMA injuries involving 34 trauma centers in the US over 10 years. Outcomes variables, both continuous and dichotomous, were analyzed initially with univariate methods. For the subsequent multivariate analysis, stepwise logistic regression was used to identify a set of risk factors significantly associated with mortality. RESULTS: There were 250 patients enrolled, with a mean Revised Trauma Score (RTS) of 6.44 and a mean Injury Severity Score (ISS) of 25. Surgical management consisted of ligation in 175 of 244 patients (72{\%}), first degree repair in 53 of 244 patients (22{\%}), autogenous grafts were used in 10 of 244 (4{\%}), and prosthetic grafts of PTFE in 6 of 244 patients (2{\%}). Overall mortality was 97 of 250 patients (39{\%}). Mortality versus Fullen's zones: zone I, 39 of 51 (76.5{\%}); zone II, 15 of 34 (44.1{\%}); zone III, 11 of 40 (27.5{\%}); and zone IV, 25 of 108 (23.1{\%}). Mortality versus Fullen's ischemia grade: grade 1, 22 of 34 (64.7{\%}). Mortality versus AAST-OIS for abdominal vascular injury: grade I, 9 of 55 (16.4{\%}); grade II, 13 of 51 (25.5{\%}); grade III, 8 of 20 (40{\%}); grade IV, 37 of 69 (53.6{\%}); and grade V, 17 of 19 (89.5{\%}). Logistic regression analysis identified as independent risk factors for mortality the following: transfusion of greater than 10 units of packed RBCs, intraoperative acidosis, dysrhythmias, injury to Fullen's zone I or II, and multisystem organ failure. CONCLUSIONS: SMA injuries are highly lethal. Fullen's anatomic zones, ischemia grade, and AAST-OIS abdominal vascular injuries correlate well with mortality. Injuries to Fullen's zones I and II, Fullen's maximal ischemia grade, and AAST-OIS injury grades IV and V, high-intraoperative transfusion requirements, and presence of acidosis and disrhythmias are significant predictors of mortality. All of these predictive factors for mortality must be taken into account in the surgical management of these injuries.",
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T1 - Multiinstitutional experience with the management of superior mesenteric, artery injuries

AU - Asensio, Juan A.

AU - Britt, L. D.

AU - Borzotta, Anthony

AU - Peitzman, Andrew

AU - Miller, Frank B.

AU - Mackersie, Robert C.

AU - Pasquale, Michael D.

AU - Pachter, H. Leon

AU - Hoyt, David B.

AU - Rodriguez, Jorge L.

AU - Falcone, Robert

AU - Davis, Kimberly

AU - Anderson, John T

AU - Ali, Jameel

AU - Chan, Linda

PY - 2001

Y1 - 2001

N2 - BACKGROUND: Superior mesenteric artery (SMA) injuries are rare and often lethal injuries incurring very high morbidity and mortality. The purposes of this study are to review a multiinstitutional experience with these injuries; to analyze Fullen's classification based on anatomic zone and ischemia grade for its predictive value; to correlate the American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) for abdominal vascular injury with mortality; and to identify independent risk factors predictive of mortality, describing current trends for the management of this injury in America. STUDY DESIGN: We performed a retrospective, multiinstitutional study of patients sustaining SMA injuries involving 34 trauma centers in the US over 10 years. Outcomes variables, both continuous and dichotomous, were analyzed initially with univariate methods. For the subsequent multivariate analysis, stepwise logistic regression was used to identify a set of risk factors significantly associated with mortality. RESULTS: There were 250 patients enrolled, with a mean Revised Trauma Score (RTS) of 6.44 and a mean Injury Severity Score (ISS) of 25. Surgical management consisted of ligation in 175 of 244 patients (72%), first degree repair in 53 of 244 patients (22%), autogenous grafts were used in 10 of 244 (4%), and prosthetic grafts of PTFE in 6 of 244 patients (2%). Overall mortality was 97 of 250 patients (39%). Mortality versus Fullen's zones: zone I, 39 of 51 (76.5%); zone II, 15 of 34 (44.1%); zone III, 11 of 40 (27.5%); and zone IV, 25 of 108 (23.1%). Mortality versus Fullen's ischemia grade: grade 1, 22 of 34 (64.7%). Mortality versus AAST-OIS for abdominal vascular injury: grade I, 9 of 55 (16.4%); grade II, 13 of 51 (25.5%); grade III, 8 of 20 (40%); grade IV, 37 of 69 (53.6%); and grade V, 17 of 19 (89.5%). Logistic regression analysis identified as independent risk factors for mortality the following: transfusion of greater than 10 units of packed RBCs, intraoperative acidosis, dysrhythmias, injury to Fullen's zone I or II, and multisystem organ failure. CONCLUSIONS: SMA injuries are highly lethal. Fullen's anatomic zones, ischemia grade, and AAST-OIS abdominal vascular injuries correlate well with mortality. Injuries to Fullen's zones I and II, Fullen's maximal ischemia grade, and AAST-OIS injury grades IV and V, high-intraoperative transfusion requirements, and presence of acidosis and disrhythmias are significant predictors of mortality. All of these predictive factors for mortality must be taken into account in the surgical management of these injuries.

AB - BACKGROUND: Superior mesenteric artery (SMA) injuries are rare and often lethal injuries incurring very high morbidity and mortality. The purposes of this study are to review a multiinstitutional experience with these injuries; to analyze Fullen's classification based on anatomic zone and ischemia grade for its predictive value; to correlate the American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS) for abdominal vascular injury with mortality; and to identify independent risk factors predictive of mortality, describing current trends for the management of this injury in America. STUDY DESIGN: We performed a retrospective, multiinstitutional study of patients sustaining SMA injuries involving 34 trauma centers in the US over 10 years. Outcomes variables, both continuous and dichotomous, were analyzed initially with univariate methods. For the subsequent multivariate analysis, stepwise logistic regression was used to identify a set of risk factors significantly associated with mortality. RESULTS: There were 250 patients enrolled, with a mean Revised Trauma Score (RTS) of 6.44 and a mean Injury Severity Score (ISS) of 25. Surgical management consisted of ligation in 175 of 244 patients (72%), first degree repair in 53 of 244 patients (22%), autogenous grafts were used in 10 of 244 (4%), and prosthetic grafts of PTFE in 6 of 244 patients (2%). Overall mortality was 97 of 250 patients (39%). Mortality versus Fullen's zones: zone I, 39 of 51 (76.5%); zone II, 15 of 34 (44.1%); zone III, 11 of 40 (27.5%); and zone IV, 25 of 108 (23.1%). Mortality versus Fullen's ischemia grade: grade 1, 22 of 34 (64.7%). Mortality versus AAST-OIS for abdominal vascular injury: grade I, 9 of 55 (16.4%); grade II, 13 of 51 (25.5%); grade III, 8 of 20 (40%); grade IV, 37 of 69 (53.6%); and grade V, 17 of 19 (89.5%). Logistic regression analysis identified as independent risk factors for mortality the following: transfusion of greater than 10 units of packed RBCs, intraoperative acidosis, dysrhythmias, injury to Fullen's zone I or II, and multisystem organ failure. CONCLUSIONS: SMA injuries are highly lethal. Fullen's anatomic zones, ischemia grade, and AAST-OIS abdominal vascular injuries correlate well with mortality. Injuries to Fullen's zones I and II, Fullen's maximal ischemia grade, and AAST-OIS injury grades IV and V, high-intraoperative transfusion requirements, and presence of acidosis and disrhythmias are significant predictors of mortality. All of these predictive factors for mortality must be taken into account in the surgical management of these injuries.

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