Abstract
Choroidal neovascularization membrane (CNVM) is a significant cause of ocular morbidity. Immunologic mechanisms have been proposed in the development of these lesions in exudative age related macular degeneration. Here, we describe the case of an 81-year-old man receiving ipilimumab, an immune modulating drug that enhances T cell response, for metastatic melanoma who developed three simultaneous CNVM bilaterally. This is the first case of ipilimumab-associated CNVM as well as the first case of an immune modulating drug possibly causing CNVM to our knowledge.
Original language | English (US) |
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Pages (from-to) | 341-343 |
Number of pages | 3 |
Journal | Cutaneous and Ocular Toxicology |
Volume | 32 |
Issue number | 4 |
DOIs | |
State | Published - Oct 2013 |
Keywords
- Age related macular degeneration
- Choroidal neovascularization
- Drug reaction
- Immunology
- Ipilimumab
- Melanoma
- T cell
ASJC Scopus subject areas
- Toxicology