Mucin secreting cholangiocarcinoma associated with clonorchiasis. A case report

Hepatic clonorchiasis is implicated in the pathogenesis of mucin secreting cholangiocarcinoma in the Far East. Obstructive jaundice is often associated with the malignant stricture. We present a case with recurrent cholangitis due to biliary obstruction caused by excessive mucus produced by the tumor. The excess mucus and infected bile led to early stent clogging within a few weeks after stent insertion. Intraductal 5-fluorouracil treatment resulted in an apparent reduction in mucus production. Apart from frequent admission for stent exchange, the patient has lived a reasonably good quality life for three years.