MR-guided focused ultrasound surgery, present and future

David Schlesinger, Stanley H Benedict, Chris Diederich, Wladyslaw Gedroyc, Alexander Klibanov, James Larner

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

MR-guided focused ultrasound surgery (MRgFUS) is a quickly developing technology with potential applications across a spectrum of indications traditionally within the domain of radiation oncology. Especially for applications where focal treatment is the preferred technique (for example, radiosurgery), MRgFUS has the potential to be a disruptive technology that could shift traditional patterns of care. While currently cleared in the United States for the noninvasive treatment of uterine fibroids and bone metastases, a wide range of clinical trials are currently underway, and the number of publications describing advances in MRgFUS is increasing. However, for MRgFUS to make the transition from a research curiosity to a clinical standard of care, a variety of challenges, technical, financial, clinical, and practical, must be overcome. This installment of the Vision 20/20 series examines the current status of MRgFUS, focusing on the hurdles the technology faces before it can cross over from a research technique to a standard fixture in the clinic. It then reviews current and near-term technical developments which may overcome these hurdles and allow MRgFUS to break through into clinical practice.

Original languageEnglish (US)
Article number080901
JournalMedical Physics
Volume40
Issue number8
DOIs
StatePublished - Aug 2013

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Technology
Radiation Oncology
Exploratory Behavior
Radiosurgery
Leiomyoma
Standard of Care
Publications
Research Design
Clinical Trials
Neoplasm Metastasis
Bone and Bones
Therapeutics
Research

Keywords

  • ablative therapy
  • focused ultrasound surgery
  • HIFU
  • high-intensity ultrasound
  • minimally invasive therapy
  • neuromodulation
  • thermal therapy

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Schlesinger, D., Benedict, S. H., Diederich, C., Gedroyc, W., Klibanov, A., & Larner, J. (2013). MR-guided focused ultrasound surgery, present and future. Medical Physics, 40(8), [080901]. https://doi.org/10.1118/1.4811136

MR-guided focused ultrasound surgery, present and future. / Schlesinger, David; Benedict, Stanley H; Diederich, Chris; Gedroyc, Wladyslaw; Klibanov, Alexander; Larner, James.

In: Medical Physics, Vol. 40, No. 8, 080901, 08.2013.

Research output: Contribution to journalArticle

Schlesinger, D, Benedict, SH, Diederich, C, Gedroyc, W, Klibanov, A & Larner, J 2013, 'MR-guided focused ultrasound surgery, present and future', Medical Physics, vol. 40, no. 8, 080901. https://doi.org/10.1118/1.4811136
Schlesinger D, Benedict SH, Diederich C, Gedroyc W, Klibanov A, Larner J. MR-guided focused ultrasound surgery, present and future. Medical Physics. 2013 Aug;40(8). 080901. https://doi.org/10.1118/1.4811136
Schlesinger, David ; Benedict, Stanley H ; Diederich, Chris ; Gedroyc, Wladyslaw ; Klibanov, Alexander ; Larner, James. / MR-guided focused ultrasound surgery, present and future. In: Medical Physics. 2013 ; Vol. 40, No. 8.
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