Abstract
Translocation of peptidyl-tRNA and mRNA within the ribosome during protein synthesis is promoted by the elongation factor EF-G and by the hydrolysis of GTP. A new study reports that EF-G binds to ribosomes as an EF-G·GDP complex and that GTP is exchanged for GDP on the ribosome. Together with cryo-electron microscopy, this unexpected finding helps clarify the role of GTP in translocation.
| Original language | English (US) |
|---|---|
| Article number | 8 |
| Journal | Journal of Biology |
| Volume | 4 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2005 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)
- Medicine(all)
Fingerprint Dive into the research topics of 'Movement in ribosome translocation'. Together they form a unique fingerprint.
Cite this
Fraser, C. S., & Hershey, J. W. B. (2005). Movement in ribosome translocation. Journal of Biology, 4(2), [8]. https://doi.org/10.1186/jbiol27